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Protein basic information

LiverAtlas Protein ID

HuLPr06132

Uniprot ID

B2RC97_HUMAN

Uniprot Acc

B2RC97;

Protein name

cDNA, FLJ95925, highly similar to Homo sapiens cold autoinflammatory syndrome 1 (CIAS1), mRNA

Comment

SIMILARITY:Contains 1 DAPIN domain.

Gene name

NLR family, pyrin domain containing 3

Protein sequence

MASTRCKLARYLEDLEDVDLKKFKMHLEDYPPQKGCIPLP RGQTEKADHVDLATLMIDFNGEEKAWAMAVWIFAAINRR DLYEKAKRDEPKWGSDNARVSNPTVICQEDSIEEEWMGL LEYLSRISICKMKKDYRKKYRKYVRSRFQCIEDRNARLG ESVSLNKRYTRLRLIKEHRSQQEREQELLAIGKTKTCES PVSPIKMELLFDPDDEHSEPVHTVVFQGAAGIGKTILAR KMMLDWASGTLYQDRFDYLFYIHCREVSLVTQRSLGDLI MSCCPDPNPPIHKIVRKPSRILFLMDGFDELQGAFDEHI GPLCTDWQKAERGDILLSSLIRKKLLPEASLLITTRPVA LEKLQHLLDHPRHVEILGFSEAKRKEYFFKYFSDEAQAR AAFSLIQENEVLFTMCFIPLVCWIVCTGLKQQMESGKSL AQTSKTTTAVYVFFLSSLLQPRGGSQEHGLCAHLWGLCS LAADGIWNQKILFEESDLRNHGLQKADVSAFLRMNLFQK EVDCEKFYSFIHVTFQEFFAAMYYLLEEEKEGRTNVPGS RLKLPSRDVTVLLENYGKFEKGYLIFVVRFLFGLVNQER TSYLEKKLSCKISQQIRLELLKWIEVKAKAKKLQIQPSQ LELFYCLYEMQEEDFVQRAMDYFPKIEINLSTRMDHMVS SFCIENCHRVESLSLGFLHNMPKEEEEEEKEGRHLDMVQ CVLPSSSHAACSHGLVNSHLTSSFCRGLFSVLSTSQSLT ELDLSDNSLGDPGMRVLCETLQHPGCNIRRLWLGRCGLS HECCFDISLVLSSNQKLVELDLSDNALGDFGIRLLCVGL KHLLCNLKKLWLVSCCLTSACCQDLASVLSTSHSLTRLY VGENALGDSGVAILCEKAKNPQCNLQKLGLVNSGLTSVC CSALSSVLSTNQNLTHLYLRGNTLGDKGIKLLCEGLLHP DCKLQVLELDNCNLTSHCCWDLSTLLTSSQSLRKLSLGN NDLGDLGVMMFCEVLKQQSCLLQN

Database cross reference

RefSeq Protein accession:NP_001073289
RefSeq Protein gi:119395764

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW.

Pathway

Pathway name

TCR