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Protein basic information

LiverAtlas Protein ID

HuLPr06194

Uniprot ID

B2RCW8_HUMAN

Uniprot Acc

B2RCW8;

Protein name

cDNA, FLJ96343, highly similar to Homo sapiens gamma-aminobutyric acid (GABA) A receptor, beta 3 (GABRB3), transcript variant 2,

Comment

SUBCELLULAR LOCATION:Membrane; Multi-pass membrane protein (By similarity).||SIMILARITY:Belongs to the ligand-gated ion channel (TC 1.A.9) family.

Subcellular localization

Membrane;Multi-pass membrane protein(By similarity).

Gene name

gamma-aminobutyric acid (GABA) A receptor, beta 3

Protein sequence

MCSGLLELLLPIWLSWTLGTRGSEPRSVNDPGNMSFVKET VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVN MDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWV PDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITT TAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGG DKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSL SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAA RVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGC LVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKND RSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNS AISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRR RSSQLKIKIPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN

Database cross reference

RefSeq Protein accession:NP_000805
RefSeq Protein gi:4503867

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0030054;C:cell junction;IEA:UniProtKB-KW. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0045211;C:postsynaptic membrane;IEA:UniProtKB-KW.

GO-F

GO:0005230;F:extracellular ligand-gated ion channel activity;IEA:InterPro. GO:0004890;F:GABA-A receptor activity;IEA:InterPro.