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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr07511

Uniprot ID

B3KTS4_HUMAN

Uniprot Acc

B3KTS4;

Protein name

cDNA FLJ38665 fis, clone HLUNG2003378, highly similar to Rho guanine nucleotide exchange factor 16

Comment

SIMILARITY:Contains 1 DH (DBL-homology) domain.||SIMILARITY:Contains 1 PH domain.||SIMILARITY:Contains 1 SH3 domain.

Gene name

Rho guanine nucleotide exchange factor (GEF) 16

Protein sequence

MAQRHSDSSLEEKLLGHRFHSELRLDAGGNPASGLPMVRG SPRVRDDAAFQPQVPAPPQPRPPGHEEPWPIVLSTESPA ALKLGTQQLIPKSLAVASKAKTPARHQSFGAAVLSREAA RRDPKLLPAPSFSLDDMDVDKDPGGMLRRNLRNQSYRAA MKGLGKPGGQGDAIQLSPKLQALAEEPSQPHTRSPAKNK KTLGRKRGHKGSFKDDPQLYQEIQERGLNTSQESDDDIL DESSSPEGTQKVDATIVVKSYRPAQVTWSQLPEVVELGI LDQLSTEERKRQEAMFEILTSEFSYQHSLSILVEEFLQS KELRATVTQMEHHHLFSNILDVLGASQRFFEDLEQRHKA QVLVEDISDILEEHAEKYFHPYIAYCSNEVYQQRTLQKL ISSNAAFREALREIERRPACGGLPMLSFLILPMQRVTRL PLLMDTLRLKTQGHSERYKAASRALKAISKLVRQCNEGA HRMERMEQMYTLHTQLDFSKVKSLPLISASRWLLKRGEL FLVEETGLFRKIASRPTCYLFLFNDVLVVTKKKSEESYM VQDYAQMNHIQVEKIEPSELPLPGGGNRSSSVPHPFQVT LLRNSEGRQEQLLLSSDSASDRARWIVALTHSERQWQGL SSKGDLPQVEITKAFFAKQADEVTLQQADVVLVLQQEDG WLYGERLRDGETGWFPEDFARFITSRVAVEGNVRRMERLRVETDV

Database cross reference

RefSeq Protein accession:NP_055263
RefSeq Protein gi:163792208

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005622;C:intracellular;IEA:InterPro.

GO-F

GO:0005089;F:Rho guanyl-nucleotide exchange factor activity;IEA:InterPro.

GO-P

GO:0035023;P:regulation of Rho protein signal transduction;IEA:InterPro.

Pathway

Pathway name

TGF_beta_Receptor