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Protein basic information

LiverAtlas Protein ID

HuLPr07568

Uniprot ID

B3KU69_HUMAN

Uniprot Acc

B3KU69;

Protein name

cDNA FLJ39269 fis, clone OCBBF2010420, highly similar to Guanylate cyclase soluble subunit alpha-3 (EC 4.6.1.2)

Comment

SIMILARITY:Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.

Gene name

guanylate cyclase 1, soluble, alpha 3

Protein sequence

MFCTKLKDLKITGECPFSLLAPGQVPNESSEEAAGSSESC KATVPICQDIPEKNIQESLPQRKTSRSRVYLHTLAESIC KLIFPEFERLNVALQRTLAKHKIKESRKSLEREDFEKTI AEQAVAAGVPVEVIKESLGEEVFKICYEEDENILGVVGG TLKDFLNSFSTLLKQSSHCQEAGKRGRLEDASILCLDKE DDFLHVYYFFPKRTTSLILPGIIKAAAHVLYETEVEVSL MPPCFHNDCSEFVNQPYLLYSVHMKSTKPSLSPSKPQSS LVIPTSLFCKTFPFHFMFDKDMTILQFGNGIRRLMNRGD FQGKPNFEEYFEILTPKINQTFSGIMTMLNMQFVVRVRR WDNSVKKSSRVMDLKGQMIYIVESSAILFLGSPCVDRLE DFTGRGLYLSDIPIHNALRDVVLIGEQARAQDGLKKRLG KLKATLEQAHQALEEEKKKTVDLLCSIFPCEVAQQLWQG QVVQAKKFSNVTMLFSDIVGFTAICSQCSPLQVITMLNA LYTRFDQQCGELDVYKVETIGDAYCVAGGLHKESDTHAV QIALMALKMMELSDEVMSPHGEPIKMRIGLHSGSVFAGV VGVKMPRYCLFGNNVTLANKFESCSVPRKINVSPTTYRL LKDCPGFVFTPRSREELPPNFPSEIPGICHFLDAYQQGT NSKPCFQKKDVEDGNANFLGKASGID

Database cross reference

RefSeq Protein accession:NP_000847
RefSeq Protein gi:67763816

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-F

GO:0004383;F:guanylate cyclase activity;IEA:InterPro. GO:0020037;F:heme binding;IEA:InterPro. GO:0000166;F:nucleotide binding;IEA:UniProtKB-KW.

GO-P

GO:0035556;P:intracellular signal transduction;IEA:InterPro.