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Protein basic information

LiverAtlas Protein ID

HuLPr07824

Uniprot ID

B3KW89_HUMAN

Uniprot Acc

B3KW89;

Protein name

cDNA FLJ42556 fis, clone BRACE3005760, highly similar to Active breakpoint cluster region-related protein

Comment

SIMILARITY:Contains 1 C2 domain.||SIMILARITY:Contains 1 DH (DBL-homology) domain.||SIMILARITY:Contains 1 PH domain.||SIMILARITY:Contains 1 Rho-GAP domain.

Gene name

active BCR-related gene

Protein sequence

MPYIDESPTMSPQLSARSQGGGDGVSPTPPEGLAPGVEAG KGLEMRKLVLSGFLASEEIYINQLEALLLPMKPLKATAT TSQPVLTIQQIETIFYKIQDIYEIHKEFYDNLCPKVQQW DSQVTMGHLFQKLASQLGVYKAFVDNYKVALETAEKCSQ SNNQFQKISEELKVKGPKDSKDSHTSVTMEALLYKPIDR VTRSTLVLHDLLKHTPVDHPDYPLLQDALRISQNFLSSI NEDIDPRRTAVTTPKGETRQLVKDGFLVEVSESSRKLRH VFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPLADLVFPS PEESEASPQVHPFPDHELEDMKMKISALKSEIQKEKANK GQSRAIERLKKKMFENEFLLLLNSPTIPFRIHNRNGKSY LFLLSSDYERSEWREAIQKLQKKDLQAFVLSSVELQVLT GSCFKLKTVHNIPVTSNKDDDESPGLYGFLHVIVHSAKG FRQSANLYCTLEVDSFGYFVSKAKTRVFRDTAEPKWDEE FEIELEGSQSLRILCYEKCYDKTKVNKDNNEIVDKIMGK GQIQLDPQTVETKNWHTDVIEMNGIKVEFSMKFTSRDMS LKRTPSKKQTGVFGVKISVVTKRERSKVPYIVRQCVEEV EKRGIEEVGIYRISGVATDIQALKAVFDANNKDILLMLS DMDINAIAGTLKLYFRELPEPLLTDRLYPAFMEGIALSD PAAKENCMMHLLRSLPDPNLITFLFLLEHLKRVAEKEPI NKMSLHNLATVFGPTLLRPSEVESKAHLTSAADIWSHDV MAQVQVLLYYLQHPPISFAELKRNTLYFSTDV

Database cross reference

RefSeq Protein accession:NP_001083
RefSeq Protein gi:38679954

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005622;C:intracellular;IEA:InterPro.

GO-F

GO:0005096;F:GTPase activator activity;IEA:UniProtKB-KW. GO:0005089;F:Rho guanyl-nucleotide exchange factor activity;IEA:InterPro.

GO-P

GO:0035556;P:intracellular signal transduction;IEA:InterPro. GO:0035023;P:regulation of Rho protein signal transduction;IEA:InterPro.