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Protein basic information

LiverAtlas Protein ID

HuLPr08403

Uniprot ID

B4DG39_HUMAN

Uniprot Acc

B4DG39;

Protein name

Glucose-6-phosphate isomerase

Comment

CATALYTIC ACTIVITY:D-glucose 6-phosphate = D-fructose 6- phosphate.||PATHWAY:Carbohydrate degradation; glycolysis; D-glyceraldehyde 3- phosphate and glycerone phosphate from D-glucose:step 2/4.||SUBCELLULAR LOCATION:Cytoplasm (By similarity).||SIMILARITY:Belongs to the GPI family.

Subcellular localization

Cytoplasm(By similarity).

Gene name

glucose-6-phosphate isomerase

Protein sequence

MVALCSLQHLGSSDPRALPTLPTATSGQRPAKRRRKSPAM AALTRDPQFQKLQQWYREHRSELNLRRLFDANKDRFNHF SLTLNTNHGHILVDYSKNLVTEDVMRMLVDLAKSRGVEA ARERMFNGEKINYTEGRAVLHVALRNRSNTPILVDGKDV MPEVNKVLDKMKSFCQGPLMVTEALKPYSSGGPRVWYVS NIDGTHIAKTLAQLNPESSLFIIASKTFTTQETITNAET AKEWFLQAAKDPSAVAKHFVALSTNTTKVKEFGIDPQNM FEFWDWVGGRYSLWSAIGLSIALHVGFDNFEQLLSGAHW MDQHFRTTPLEKNAPVLLALLGIWYINCFGCETHAMLPY DQYLHRFAAYFQQGDMESNGKYITKSGTRVDHQTGPIVW GEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKG LHHKILLANFLAQTEALMRGKSTEEARKELQAAGKSPED LERLLPHKVFEGNRPTNSIVFTKLTPFMLGALVAMYEHK IFVQGIIWDINSFDQWGVELGKQLAKKIEPELDGSAQVT SHDASTNGLINFIKQQREARVQ

Database cross reference

RefSeq Protein accession:NP_000166
RefSeq Protein gi:18201905

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005737;C:cytoplasm;IDA:HPA. GO:0005634;C:nucleus;IDA:HPA. GO:0005886;C:plasma membrane;IDA:HPA.

GO-F

GO:0004347;F:glucose-6-phosphate isomerase activity;IEA:HAMAP.

GO-P

GO:0006094;P:gluconeogenesis;IEA:HAMAP. GO:0006096;P:glycolysis;IEA:HAMAP.