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Protein basic information

LiverAtlas Protein ID

HuLPr08436

Uniprot ID

B4DGE4_HUMAN

Uniprot Acc

B4DGE4;

Protein name

cDNA FLJ54479, highly similar to Delta-1-pyrroline-5-carboxylatedehydrogenase, mitochondrial (EC 1.5.1.12)

Comment

SIMILARITY:Belongs to the aldehyde dehydrogenase family.

Gene name

aldehyde dehydrogenase 4 family, member A1

Protein sequence

MEAIPCVVGDEEVWTSDVQYQVSPFNHGHKVAKFCYADKS LLNKAIEAALAARKEWDLKPIADRAQIFLKAADMLSGPR RAEILAKTMVGQGKTVIQAEIDAAAELIDFFRFNAKYAV ELEGQQPISVPPSTNSTVYRGLEGFVAAISPFNFTAIGG NLAGAPALMGNVVLWKPSDTAMLASYAVYRILREAGLPP NIIQFVPADGPLFGDTVTSSEHLCGINFTGSVPTFKHLW KQVAQNLDRFHTFPRLAGECGGKNFHFVHRSADVESVVS GTLRSAFEYGGQKCSACSRLYVPHSLWPQIKGRLLEEHS RIKVGDPAEDFGTFFSAVIDAKSFARIKKWLEHARSSPS LTILAGGKCDDSVGYFVEPCIVESKDPQEPIMKEEIFGP VLSVYVYPDDKYKETLQLVDSTTSYGLTGAVFSQDKDVV QEATKVLRNAAGNFYINDKSTGSIVGQQPFGGARASGTN DKPGGPHYILRWTSPQVIKETHKPLGDWSYAYMQ

Database cross reference

RefSeq Protein accession:NP_001154976
RefSeq Protein gi:238859541

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005759;C:mitochondrial matrix;IEA:InterPro.

GO-F

GO:0003842;F:1-pyrroline-5-carboxylate dehydrogenase activity;IEA:InterPro.

GO-P

GO:0055114;P:oxidation-reduction process;IEA:UniProtKB-KW. GO:0006561;P:proline biosynthetic process;IEA:InterPro.