Protein basic information
LiverAtlas Protein ID |
HuLPr08450 |
Uniprot ID |
|
Uniprot Acc |
B4DGK3; |
Protein name |
Ubiquitin carboxyl-terminal hydrolase |
Comment |
CATALYTIC ACTIVITY:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.||SIMILARITY:Belongs to the peptidase C19 family. |
Gene name |
|
Protein sequence
|
METRKKDGTWPSAQLHVMNNNMSEEDEDFKGQPGICGLTN LGNTCFMNSALQCLSNVPQLTEYFLNNCYLEELNFRNPL GMKGEIAEAYADLVKQAWSGHHRSIVPHVFKNKVGHFAS QFLGYQQHDSQELLSFLLDGLHEDLNRVKKKEYVELCDA AGRPDQEVAQEAWQNHKRRNDSVIVDTFHGLFKSTLVCP DCGNVSVTFDPFCYLSVPLPISHKRVLEVFFIPMDPRRK PEQHRLVVPKKGKISDLCVALSKHTGISPERMMVADVFS HRFYKLYQLEEPLSSILDRDDIFVYEVSGRIEAIEGSRE DIVVPVYLRERTPARDYNNSYYGLMLFGHPLLVSVPRDR FTWEGLYNVLMYRLSRYVTKPNSDDEDDGDEKEDDEEDK DDVPGPSTGGSLRDPEPEQAGPSSGVTNRCPFLLDNCLG TSQWPPRRRRKQLFTLQTVNSNGTSDRTTSPEEVHAQPY IAIDWEPEMKKRYYDEVEAEGYVKHDCVGYVMKKAPVRL QECIELFTTVETLEKENPWYCPSCKQHQLATKKLDLWML PEILIIHLKRFSYTKFSREKLDTLVEFPIRDLDFSEFVI QPQNESNPELYKYDLIAVSNHYGGMRDGHYTTFACNKDS GQWHYFDDNSVSPVNENQIESKAAYVLFYQRQDVARRLL SPAGSSGAPASPACSSPPSSEFMDVN |
Database cross reference |
RefSeq Protein accession:NP_004642
|
Liver relevance
HLPP validation |
Yes/No |
Yes |
Project name |
French Liver;Human Liver Organelles; |
Ontology annotation
GO-F |
GO:0008234;F:cysteine-type peptidase activity;IEA:UniProtKB-KW. GO:0004221;F:ubiquitin thiolesterase activity;IEA:EC. |
GO-P |
GO:0006511;P:ubiquitin-dependent protein catabolic process;IEA:InterPro. |