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Protein basic information

LiverAtlas Protein ID

HuLPr10513

Uniprot ID

B4E168_HUMAN

Uniprot Acc

B4E168;

Protein name

Adenosylhomocysteinase

Comment

CATALYTIC ACTIVITY:S-adenosyl-L-homocysteine + H(2)O = L- homocysteine + adenosine.||COFACTOR:NAD (By similarity).||PATHWAY:Amino-acid biosynthesis; homocysteine biosynthesis; L- homocysteine from S-adenosyl-L-homocysteine:step 1/1.||SIMILARITY:Belongs to the adenosylhomocysteinase family.

Gene name

adenosylhomocysteinase-like 1

Protein sequence

MQEFTKFPTKTGRRSLSRSISQSSTDSYSSAASYTDSSDD EVSPREKQQTNSKGSSNFCVKNIKQAEFGRREIEIAEQD MSALISLRKRAQGEKPLAGAKIVGCTHITAQTAVLIETL CALGAQCRWSACNIYSTQNEVAAALAEAGVAVFAWKGES EDDFWWCIDRCVNMDGWQANMILDDGGDLTHWVYKKYPN VFKKIRGIVEESVTGVHRLYQLSKAGKLCVPAMNVNDSV TKQKFDNLYCCRESILDGLKRTTDVMFGGKQVVVCGYGE VGKGCCAALKALGAIVYITEIDPICALQACMDGFRVVKL NEVIRQVDVVITCTGNKNVVTREHLDRMKNSCIVCNMGH SNTEIDVTSLRTPELTWERVRSQVDHVIWPDGKRVVLLA EGRLLNLSCSTVPTFVLSITATTQALALIELYNAPEGRY KQDVYLLPKKMDEYVASLHLPSFDAHLTELTDDQAKYLG LNKNGPFKPNYYRY

Database cross reference

RefSeq Protein accession:NP_006612
RefSeq Protein gi:21361647

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0004013;F:adenosylhomocysteinase activity;IEA:EC.

GO-P

GO:0006730;P:one-carbon metabolic process;IEA:UniProtKB-KW.