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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr10960

Uniprot ID

B5BU22_HUMAN

Uniprot Acc

B5BU22;

Protein name

Protein kinase C alpha type

Comment

CATALYTIC ACTIVITY:ATP + a protein = ADP + a phosphoprotein.||SIMILARITY:Contains 1 AGC-kinase C-terminal domain.||SIMILARITY:Contains 1 C2 domain.||SIMILARITY:Contains 1 protein kinase domain.

Gene name

protein kinase C, alpha

Protein sequence

MADVFPGNDSTASQDVANRFARKGALRQKNVHEVKDHKFI ARFFKQPTFCSHCTDFIWGFGKQGFQCQVCCFVVHKRCH EFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHC GSLLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTE KRGRIYLKAEVADEKLHVTVRDAKNLIPMDPNGLSDPYV KLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSD KDRRLSVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGW YKLLNQEEGEYYNVPIPEGDEEGNMELRQKFEKAKLGPA GNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGK VMLADRKGTEELYAIKILKKDVVIQDDDVECTMVEKRVL ALLDKPPFLTQLHSCFQTVDRLYFVMEYVNGGDLMYHIQ QVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNV MLDSEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPE IIAYQPYGKSVDWWAYGVLLYEMLAGQPPFDGEDEDELF QSIMEHNVSYPKSLSKEAVSICKGLMTKHPAKRLGCGPE GERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAEN FDKFFTRGQPVLTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV

Database cross reference

RefSeq Protein accession:NP_002728
RefSeq Protein gi:4506067

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0004697;F:protein kinase C activity;IEA:InterPro. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0035556;P:intracellular signal transduction;IEA:InterPro. GO:0006468;P:protein phosphorylation;IEA:InterPro.

Pathway

Pathway name

IL2