Protein basic information
LiverAtlas Protein ID |
HuLPr10973 |
Uniprot ID |
|
Uniprot Acc |
B5BU61; |
Protein name |
Histone deacetylase |
Comment |
CATALYTIC ACTIVITY:Hydrolysis of an N(6)-acetyl-lysine residue of a histone to yield a deacetylated histone.||SUBCELLULAR LOCATION:Nucleus (By similarity).||SIMILARITY:Belongs to the histone deacetylase family. HD Type 1 subfamily. |
Subcellular localization |
Nucleus(By similarity). |
Gene name |
|
Protein sequence
|
MAQTQGTRRKVCYYYDGDVGNYYYGQGHPMKPHRIRMTHN LLLNYGLYRKMEIYRPHKANAEEMTKYHSDDYIKFLRSI RPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSV ASAVKLNKQQTDIAVNWAGGLHHAKKSEASGFCYVNDIV LAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTV SFHKYGEYFPGTGDLRDIGAGKGKYYAVNYPLRDGIDDE SYEAIFKPVMSKVMEMFQPSAVVLQCGSDSLSGDRLGCF NLTIKGHAKCVEFVKSFNLPMLMLGGGGYTIRNVARCWT YETAVALDTEIPNELPYNDYFEYFGPDFKLHISPSNMTS QNTNEYLEKIKQRLFENLRMLPHAPGVQMQAIPEDAIPE ESGDEDEDDPDKRISICSSDKRIACEEEFSDSEEEGEGG RKNSSNFKKAKRVKTEDEKEKDPEEKKEVTEEEKTKEEK PEAKGVKEEVKLA |
Database cross reference |
RefSeq Protein accession:NP_004955
|
Liver relevance
HLPP validation |
Yes/No |
Yes |
Project name |
Chinese Liver; |
Ontology annotation
GO-C |
GO:0005634;C:nucleus;IDA:HPA. |
GO-F |
GO:0034739;F:histone deacetylase activity (H3-K16 specific);IEA:EC. GO:0032041;F:NAD-dependent histone deacetylase activity (H3-K14 specific);IEA:EC. GO:0046969;F:NAD-dependent histone deacetylase activity (H3-K9 specific);IEA:EC. GO:0046970;F:NAD-depen |
GO-P |
GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |