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Protein basic information

LiverAtlas Protein ID

HuLPr11420

Uniprot ID

B7Z2T5_HUMAN

Uniprot Acc

B7Z2T5;

Protein name

cDNA FLJ55427, highly similar to Sodium/potassium-transporting ATPase alpha-1 chain (EC 3.6.3.9)

Comment

SIMILARITY:Belongs to the cation transport ATPase (P-type) family.

Gene name

ATPase, Na+/K+ transporting, alpha 1 polypeptide

Protein sequence

MAFKVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVS MDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNA LTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQ AATEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKI MESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGG DRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNEN PLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLA SGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLIL EYTWLEAVILLIGIIVANVPEGLLATVTVCLTLTAKRMA RKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNR AVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKE MRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMK GAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGG LGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFV GLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACV VHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVE GCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVS KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLT SNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAI SLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGM IQALGGFFTYFVILAENGFLPIHLLGLRVDWDGRWINDV EDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVIC KTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGV ALRMYPLKPTWWFCAFPYSLLIFV

Database cross reference

RefSeq Protein accession:NP_000692
RefSeq Protein gi:21361181

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Fetal Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0015662;F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism;IEA:InterPro. GO:0015077;F:monovalent inorganic cation transmembrane transporter activity;IEA:InterPro.

GO-P

GO:0006754;P:ATP biosynthetic process;IEA:InterPro.