Protein basic information
| LiverAtlas Protein ID |
HuLPr12912 |
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Uniprot ID |
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Uniprot Acc |
Q5H9F3;B5MDQ8;Q5H9F2;Q5H9F4;Q6ZVE0;Q8TEN3;Q9Y528; |
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Protein name |
BCL-6 corepressor-like protein 1 |
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Comment |
FUNCTION:Transcriptional corepressor. May specifically inhibit gene expression when recruited to promoter regions by sequence specific DNA-binding proteins such as BCL6. This repression may be mediated at least in part by histone deacetylase activities which can associate with this corepressor.||SUBUNIT:Interacts with CTBP1. Interacts with HDAC4, HDAC5 and HDAC7.||SUBCELLULAR LOCATION:Nucleus.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q5H9F3-1; Sequence=Displayed; Name=2; IsoId=Q5H9F3-2; Sequence=VSP 029778; Name=3; IsoId=Q5H9F3-3; Sequence=VSP 029779;||TISSUE SPECIFICITY:Detected in testis and prostate. Detected at lower levels in peripheral blood leukocytes and spleen.||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.||SIMILARITY:Belongs to the BCOR family.||SIMILARITY:Contains 3 ANK repeats.||SEQUENCE CAUTION:Sequence=BAC85922.1; Type=Erroneous initiation; |
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Subcellular localization |
Nucleus. |
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Gene name |
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Protein sequence
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MISTAPLYSGVHNWTSSDRIRMCGINEERRAPLSDEESTT GDCQHFGSQEFCVSSSFSKVELTAVGSGSNARGADPDGS ATEKLGHKSEDKPDDPQPKMDYAGNVAEAEGFLVPLSSP GDGLKLPASDSAEASNSRADCSWTPLNTQMSKQVDCSPA GVKALDSRQGVGEKNTFILATLGTGVPVEGTLPLVTTNF SPLPAPICPPAPGSASVPHSVPDAFQVPLSVPAPVPHSG LVPVQVATSVPAPSPPLAPVPALAPAPPSVPTLISDSNP LSVSASVLVPVPASAPPSGPVPLSAPAPAPLSVPVSAPP LALIQAPVPPSAPTLVLAPVPTPVLAPMPASTPPAAPAP PSVPMPTPTPSSGPPSTPTLIPAFAPTPVPAPTPAPIFT PAPTPMPAATPAAIPTSAPIPASFSLSRVCFPAAQAPAM QKVPLSFQPGTVLTPSQPLVYIPPPSCGQPLSVATLPTT LGVSSTLTLPVLPSYLQDRCLPGVLASPELRSYPYAFSV ARPLTSDSKLVSLEVNRLPCTSPSGSTTTQPAPDGVPGP LADTSLVTASAKVLPTPQPLLPAPSGSSAPPHPAKMPSG TEQQTEGTSVTFSPLKSPPQLEREMASPPECSEMPLDLS SKSNRQKLPLPNQRKTPPMPVLTPVHTSSKALLSTVLSR SQRTTQAAGGNVTSCLGSTSSPFVIFPEIVRNGDPSTWV KNSTALISTIPGTYVGVANPVPASLLLNKDPNLGLNRDP RHLPKQEPISIIDQGEPKGTGATCGKKGSQAGAEGQPST VKRYTPARIAPGLPGCQTKELSLWKPTGPANIYPRCSVN GKPTSTQVLPVGWSPYHQASLLSIGISSAGQLTPSQGAP IRPTSVVSEFSGVPSLSSSEAVHGLPEGQPRPGGSFVPE QDPVTKNKTCRIAAKPYEEQVNPVLLTLSPQTGTLALSV QPSGGDIRMNQGPEESESHLCSDSTPKMEGPQGACGLKL AGDTKPKNQVLATYMSHELVLATP |
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Database cross reference |
RefSeq Protein accession:NP_068765
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver; |
Ontology annotation
| GO-C |
GO:0005737;C:cytoplasm;IDA:HPA. GO:0005634;C:nucleus;IDA:HPA. |
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GO-P |
GO:0016568;P:chromatin modification;IEA:UniProtKB-KW. GO:0006355;P:regulation of transcription, DNA-dependent;IEA:UniProtKB-KW. GO:0006351;P:transcription, DNA-dependent;IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr12912 |
PHOSPHORYLATION |
1034 |
S |
PhosphoSitePlus |
HTP |
N |
 
|
|
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HuLPr12912 |
PHOSPHORYLATION |
1042 |
S |
PhosphoSitePlus |
LTP |
N |
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HuLPr12912 |
PHOSPHORYLATION |
48 |
S |
PhosphoSitePlus |
LTP HTP |
N |
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HuLPr12912 |
PHOSPHORYLATION |
1679 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
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HuLPr12912 |
PHOSPHORYLATION |
1033 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr12912 |
PHOSPHORYLATION |
1162 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr12912 |
PHOSPHORYLATION |
613 |
S |
PhosphoSitePlus |
LTP |
N |
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