HuLPr13089

Uniprot ID

BT2A1_HUMAN

Uniprot Acc

Q7KYR7;O00475;P78408;Q7KYQ7;Q7Z386;Q9NU62;

Protein name

Butyrophilin subfamily 2 member A1

Comment

SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q7KYR7-2; Sequence=Displayed; Name=2; IsoId=Q7KYR7-1; Sequence=VSP 035843, VSP 035844; Name=3; IsoId=Q7KYR7-3; Sequence=VSP 012708; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Highly expressed in brain, bone marrow, small intestine, muscle, spleen and pancreas. Moderate expression was seen in lung, liver and kidney.||SIMILARITY:Belongs to the immunoglobulin superfamily. BTN/MOG family.||SIMILARITY:Contains 1 B30.2/SPRY domain.||SIMILARITY:Contains 1 Ig-like V-type (immunoglobulin-like) domain.||SEQUENCE CAUTION:Sequence=CAB71221.2; Type=Erroneous gene model prediction;

Subcellular localization

Membrane;Single-pass type I membrane protein(By similarity).

Gene name

butyrophilin, subfamily 2, member A1

Protein sequence

MESAAALHFSRPASLLLLLLSLCALVSAQFIVVGPTDPIL ATVGENTTLRCHLSPEKNAEDMEVRWFRSQFSPAVFVYK GGRERTEEQMEEYRGRTTFVSKDISRGSVALVIHNITAQ ENGTYRCYFQEGRSYDEAILHLVVAGLGSKPLISMRGHE DGGIRLECISRGWYPKPLTVWRDPYGGVAPALKEVSMPD ADGLFMVTTAVIIRDKSVRNMSCSINNTLLGQKKESVIF IPESFMPSVSPCAVALPIIVVILMIPIAVCIYWINKLQK EKKILSGEKEFERETREIALKELEKERVQKEEELQVKEK LQEELRWRRTFLHAVDVVLDPDTAHPDLFLSEDRRSVRR CPFRHLGESVPDNPERFDSQPCVLGRESFASGKHYWEVE VENVIEWTVGVCRDSVERKGEVLLIPQNGFWTLEMHKGQ YRAVSSPDRILPLKESLCRVGVFLDYEAGDVSFYNMRDR SHIYTCPRSAFSVPVRPFFRLGCEDSPIFICPALTGANG VTVPEEGLTLHRVGTHQSL

Database cross reference

RefSeq Protein accession:NP_001184162
RefSeq Protein gi:308522728

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Fetal Liver;Human Liver Organelles;

GO:0005887;C:integral to plasma membrane;TAS:ProtInc.

GO-P

GO:0006629;P:lipid metabolic process;TAS:ProtInc.

TGF_beta_Receptor