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Protein basic information

LiverAtlas Protein ID

HuLPr13092

Uniprot ID

BT3A1_HUMAN

Uniprot Acc

O00481;A2A278;A8K2C8;Q0P515;Q147X5;Q53F15;Q99420;Q9HCY1;

Protein name

Butyrophilin subfamily 3 member A1

Comment

SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=O00481-1; Sequence=Displayed; Name=2; IsoId=O00481-2; Sequence=VSP 012714, VSP 012715; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Highly expressed in heart, pancreas and lung, Moderately expressed in placenta, liver and muscle.||SIMILARITY:Belongs to the immunoglobulin superfamily. BTN/MOG family.||SIMILARITY:Contains 1 B30.2/SPRY domain.||SIMILARITY:Contains 2 Ig-like V-type (immunoglobulin-like) domains.||SEQUENCE CAUTION:Sequence=CAA69164.1; Type=Erroneous initiation;

Subcellular localization

Membrane;Single-pass type I membrane protein(By similarity).

Gene name

butyrophilin, subfamily 3, member A1

Protein sequence

MKMASFLAFLLLNFRVCLLLLQLLMPHSAQFSVLGPSGPI LAMVGEDADLPCHLFPTMSAETMELKWVSSSLRQVVNVY ADGKEVEDRQSAPYRGRTSILRDGITAGKAALRIHNVTA SDSGKYLCYFQDGDFYEKALVELKVAALGSDLHVDVKGY KDGGIHLECRSTGWYPQPQIQWSNNKGENIPTVEAPVVA DGVGLYAVAASVIMRGSSGEGVSCTIRSSLLGLEKTASI SIADPFFRSAQRWIAALAGTLPVLLLLLGGAGYFLWQQQ EEKKTQFRKKKREQELREMAWSTMKQEQSTRVKLLEELR WRSIQYASRGERHSAYNEWKKALFKPADVILDPKTANPI LLVSEDQRSVQRAKEPQDLPDNPERFNWHYCVLGCESFI SGRHYWEVEVGDRKEWHIGVCSKNVQRKGWVKMTPENGF WTMGLTDGNKYRTLTEPRTNLKLPKPPKKVGVFLDYETG DISFYNAVDGSHIHTFLDVSFSEALYPVFRILTLEPTALTICPA

Database cross reference

RefSeq Protein accession:NP_001138480
RefSeq Protein gi:222418658

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-P

GO:0006629;P:lipid metabolic process;TAS:ProtInc.

Pathway

Pathway name

IL2