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Protein basic information

LiverAtlas Protein ID

HuLPr13759

Uniprot ID

C9J2K4_HUMAN

Uniprot Acc

C9J2K4;

Protein name

V-type proton ATPase subunit F

Comment

FUNCTION:Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells (By similarity).||SUBUNIT:V-ATPase is an heteromultimeric enzyme composed of a peripheral catalytic V1 complex (components A to H) attached to an integral membrane V0 proton pore complex (By similarity).||SIMILARITY:Belongs to the V-ATPase F subunit family.||CAUTION:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

Gene name

ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F

Protein sequence

MAGRGKLIAVIGDEDTVTGFLLGGIGELNKNRHPNFLVVE KDTTINEIEDTFRSLGSLPGSVVEANPNQRDPPLWDEID SRQFLNRDDIGIILINQYIAEMVRHALDAHQQSIPAVLE IPSKEHPYDAAKDSILRRARGMFTAEDLR

Database cross reference

RefSeq Protein accession:NP_001185838
RefSeq Protein gi:312032453

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0033180;C:proton-transporting V-type ATPase, V1 domain;IEA:InterPro.

GO-F

GO:0046933;F:hydrogen ion transporting ATP synthase activity, rotational mechanism;IEA:InterPro. GO:0046961;F:proton-transporting ATPase activity, rotational mechanism;IEA:InterPro.

GO-P

GO:0015991;P:ATP hydrolysis coupled proton transport;IEA:InterPro.