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Protein basic information

LiverAtlas Protein ID

HuLPr14672

Uniprot ID

CBPC3_HUMAN

Uniprot Acc

Q8NEM8;B7Z827;Q9H965;

Protein name

Cytosolic carboxypeptidase 3

Comment

FUNCTION:Metallocarboxypeptidase that may play a role in the processing of tubulin.||COFACTOR:Binds 1 zinc ion per subunit (By similarity).||SUBCELLULAR LOCATION:Cytoplasm, cytosol (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q8NEM8-1; Sequence=Displayed; Name=2; IsoId=Q8NEM8-2; Sequence=VSP 024372, VSP 024373; Note=No experimental confirmation available; Name=3; IsoId=Q8NEM8-3; Sequence=VSP 024370, VSP 024371; Note=No experimental confirmation available; Name=4; IsoId=Q8NEM8-4; Sequence=VSP 040423; Note=No experimental confirmation available;||SIMILARITY:Belongs to the peptidase M14 family.

Subcellular localization

Cytoplasm, cytosol(By similarity).

Gene name

ATP/GTP binding protein-like 3

Protein sequence

MSEDSEKEDYSDRTISDEDESDEDMFMKFVSEDLHRCALL TADSFGDPFFPRTTQILLEYQLGRWVPRLREPRDLYGVS SSGPLSPTRWPYHCEVIDEKVQHIDWTPSCPEPVYIPTG LETEPLYPDSKEATVVYLAEDAYKEPCFVYSRVGGNRTP LKQPVDYRDNTLMFEARFESGNLQKVVKVAEYEYQLTVR PDLFTNKHTQWYYFQVTNMRAGIVYRFTIVNFTKPASLY SRGMRPLFYSEKEAKAHHIGWQRIGDQIKYYRNNPGQDG RHYFSLTWTFQFPHNKDTCYFAHCYPYTYTNLQEYLSGI NNDPVRSKFCKIRVLCHTLARNMVYILTITTPLKNSDSR KRKAVILTARVHPGETNSSWIMKGFLDYILGNSSDAQLL RDTFVFKVVPMLNPDGVIVGNYRCSLAGRDLNRNYTSLL KESFPSVWYTRNMVHRLMEKREVILYCDLHGHSRKENIF MYGCDGSDRSKTLYLQQRIFPLMLSKNCPDKFSFSACKF NVQKSKEGTGRVVMWKMGIRNSFTMEATFCGSTLGNKRG THFSTKDLESMGYHFCDSLLDYCDPDRTKYYRCLKELEE MERHITLEKVFEDSDTPVIDITLDVESSSRGSDSSESID SLTYLLKLTSQKKHLKTKKERNSTIASHQNARGQEVYDR GHLLQRHTQSNSDVKDTRPNEPDDYMVDYFRRQLPNQGL AHCKLRLPGSRHSPASASRVAGTTGTRHHTWLIFVFLVE MGKKIPLKGTDLYGNCFKVTSLQSPMGKQTSTWTEKTRI PTEDLHHNLKSKIKECISFQSKKTGINWTDDEKRSYKDK GIVQTQEILQYLLPIVHSTKNMQTTQIKQLFNPRTNFQI QHQLNPATCRNIKKYSTSWTAPRNHPFVIQGDVMANSSE WVQSKPHRSLESLSPLKGPKKNKHSQIWAIKNEDIKPLS SKWETASSSFGMDANVLKYKSLQAEETNQQSSKHTALHL TKNKDEQANKNDGQPTLYLKFQRE

Database cross reference

RefSeq Protein accession:NP_848658
RefSeq Protein gi:222352158

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

Ontology annotation

GO-C

GO:0005829;C:cytosol;IEA:UniProtKB-SubCell.

GO-F

GO:0004181;F:metallocarboxypeptidase activity;IDA:UniProtKB. GO:0008270;F:zinc ion binding;IEA:InterPro.

GO-P

GO:0006508;P:proteolysis;IEA:InterPro.