HuLPr15006

Uniprot ID

CD302_HUMAN

Uniprot Acc

Q8IX05;Q15009;

Protein name

CD302 antigen

Comment

SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (Potential).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=3; Name=1; IsoId=Q8IX05-1; Sequence=Displayed; Note=Produced by intergenic splicing of LY75 and CD302; Name=2; Synonyms=Fusion protein variant V34-2; IsoId=O60449-2; Sequence=External; Note=Produced by intergenic splicing of LY75 and CD302; Name=3; Synonyms=Fusion protein variant V33-2; IsoId=O60449-3; Sequence=External; Note=Produced by intergenic splicing of LY75 and CD302;||TISSUE SPECIFICITY:Expressed in myeloid and B lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.||MISCELLANEOUS:Isoform 2 and isoform 3 are produced in HRS cells by a transcriptional control mechanism which cotranscribe an mRNA containing LY75 and CD302 prior to generating the intergenically spliced mRNA to produce LY75/CD302 fusion proteins.||SIMILARITY:Contains 1 C-ty

Subcellular localization

Membrane;Single-pass type I membrane protein(Potential).

Gene name

CD302 molecule

Protein sequence

MLRAALPALLLPLLGLAAAAVADCPSSTWIQFQDSCYIFL QEAIKVESIEDVRNQCTDHGADMISIHNEEENAFILDTL KKQWKGPDDILLGMFYDTDDASFKWFDNSNMTFDKWTDQ DDDEDLVDTCAFLHIKTGEWKKGNCEVSSVEGTLCKTAI PYKRKYLSDNHILISALVIASTVILTVLGAIIWFLYKKH SDSRFTTVFSTAPQSPYNEDCVLVVGEENEYPVQFD

Database cross reference

RefSeq Protein accession:NP_001185692
RefSeq Protein gi:311771590

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0005529;F:sugar binding;IEA:UniProtKB-KW.

IL2