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Protein basic information

LiverAtlas Protein ID

HuLPr15012

Uniprot ID

CD37L_HUMAN

Uniprot Acc

Q7L3B6;B1AL70;Q9NWS3;Q9NX16;

Protein name

Hsp90 co-chaperone Cdc37-like 1

Comment

FUNCTION:Co-chaperone that binds to numerous proteins and promotes their interaction with Hsp70 and Hsp90 (By similarity).||SUBUNIT:Self-associates. Forms complexes with Hsp70 and Hsp90. Interacts with CDC37, FKBP4, PPID and STIP1.||SUBCELLULAR LOCATION:Cytoplasm.||TISSUE SPECIFICITY:Expressed in brain, heart, kidney, liver, placenta and skeletal muscle.||SIMILARITY:Belongs to the CDC37 family.||SEQUENCE CAUTION:Sequence=BAA91206.1; Type=Erroneous termination; Positions=124; Note=Translated as Cys;

Subcellular localization

Cytoplasm.

Gene name

cell division cycle 37 homolog (S. cerevisiae)-like 1

Protein sequence

MEQPWPPPGPWSLPRAEGEAEEESDFDVFPSSPRCPQLPG GGAQMYSHGIELACQKQKEFVKSSVACKWNLAEAQQKLG SLALHNSESLDQEHAKAQTAVSELRQREEEWRQKEEALV QREKMCLWSTDAISKDVFNKSFINQDKRKDTEDEDKSES FMQKYEQKIRHFGMLSRWDDSQRFLSDHPYLVCEETAKY LILWCFHLEAEKKGALMEQIAHQAVVMQFIMEMAKNCNV DPRGCFRLFFQKAKAEEEGYFEAFKNELEAFKSRVRLYS QSQSFQPMTVQNHVPHSGVGSIGLLESLPQNPDYLQYSI STALCSLNSVVHKEDDEPKMMDTV

Database cross reference

RefSeq Protein accession:NP_060383
RefSeq Protein gi:66773038

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr15012

PHOSPHORYLATION

32

S

PhosphoSitePlus

3245840

HTP

N