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Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr15629

Uniprot ID

CK2N1_HUMAN

Uniprot Acc

Q7Z7J9;

Protein name

Calcium/calmodulin-dependent protein kinase II inhibitor 1

Comment

FUNCTION:Potent and specific inhibitor of CaM-kinase II (CAMK2) (By similarity).||SUBUNIT:Interacts with CAMK2B; the presence of Ca(2+)/calmodulin increases the interaction but is not essential (By similarity).||SUBCELLULAR LOCATION:Cell junction, synapse, synaptosome. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity).||SIMILARITY:Belongs to the CAMK2N family.

Subcellular localization

Cell junction, synapse, synaptosome.Cell junction, synapse, postsynaptic cell membrane, postsynaptic density(By similarity).

Gene name

calcium/calmodulin-dependent protein kinase II inhibitor 1

Protein sequence

MSEVLPYGDEKLSPYGDGGDVGQIFSCRLQDTNNFFGAGQ NKRPPKLGQIGRSKRVVIEDDRIDDVLKNMTDKAPPGV

Database cross reference

RefSeq Protein accession:NP_061054
RefSeq Protein gi:31324543

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0030054;C:cell junction;IEA:UniProtKB-KW. GO:0014069;C:postsynaptic density;IEA:UniProtKB-SubCell. GO:0045211;C:postsynaptic membrane;IEA:UniProtKB-KW. GO:0019717;C:synaptosome;IEA:UniProtKB-SubCell.

Pathway

Pathway name

IL2