Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr15733

Uniprot ID

CLD20_HUMAN

Uniprot Acc

P56880;

Protein name

Claudin-20

Comment

FUNCTION:Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium- independent cell-adhesion activity (By similarity).||SUBCELLULAR LOCATION:Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.||SIMILARITY:Belongs to the claudin family.

Subcellular localization

Cell junction, tight junction.Cell membrane;Multi-pass membrane protein.

Gene name

claudin 20

Protein sequence

MASAGLQLLAFILALSGVSGVLTATLLPNWKVNVDVDSNI ITAIVQLHGLWMDCTWYSTGMFSCALKHSILSLPIHVQA ARATMVLACVLSALGICTSTVGMKCTRLGGDRETKSHAS FAGGVCFMSAGISSLISTVWYTKEIIANFLDLTVPESNK HEPGGAIYIGFISAMLLFISGMIFCTSCIKRNPEARLDP PTQQPISNTQLENNSTHNLKDYV

Database cross reference

RefSeq Protein accession:NP_001001346
RefSeq Protein gi:47716519

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005923;C:tight junction;ISS:UniProtKB.

GO-F

GO:0042802;F:identical protein binding;ISS:UniProtKB. GO:0005198;F:structural molecule activity;IEA:InterPro.

GO-P

GO:0016338;P:calcium-independent cell-cell adhesion;ISS:UniProtKB. GO:0070830;P:tight junction assembly;TAS:Reactome.