Protein basic information
| LiverAtlas Protein ID |
HuLPr15754 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q9UDT6;O14527;O43611; |
|
Protein name |
CAP-Gly domain-containing linker protein 2 |
|
Comment |
FUNCTION:Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operates in the control of brain-specific organelle translocations (By similarity).||SUBUNIT:Interacts with CLASP1 and CLASP2.||SUBCELLULAR LOCATION:Cytoplasm (By similarity). Cytoplasm, cytoskeleton (By similarity). Note=Associated with the cytoskeleton (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9UDT6-1; Sequence=Displayed; Name=2; IsoId=Q9UDT6-2; Sequence=VSP 015682;||DISEASE:Note=CLIP2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of CLIP2 may be the cause of certain car |
|
Subcellular localization |
Cytoplasm(By similarity).Cytoplasm, cytoskeleton(By similarity). |
|
Gene name |
|
|
Protein sequence
|
MQKPSGLKPPGRGGKHSSPMGRTSTGSASSSAAVAASSKE GSPLHKQSSGPSSSPAAAAAPEKPGPKAAEVGDDFLGDF VVGERVWVNGVKPGVVQYLGETQFAPGQWAGVVLDDPVG KNDGAVGGVRYFECPALQGIFTRPSKLTRQPTAEGSGSD AHSVESLTAQNLSLHSGTATPPLTSRVIPLRESVLNSSV KTGNESGSNLSDSGSVKRGEKDLRLGDRVLVGGTKTGVV RYVGETDFAKGEWCGVELDEPLGKNDGAVAGTRYFQCPP KFGLFAPIHKVIRIGFPSTSPAKAKKTKRMAMGVSALTH SPSSSSISSVSSVASSVGGRPSRSGLLTETSSRYARKIS GTTALQEALKEKQQHIEQLLAERDLERAEVAKATSHICE VEKEIALLKAQHEQYVAEAEEKLQRARLLVESVRKEKVD LSNQLEEERRKVEDLQFRVEEESITKGDLETQTQLEHAR IGELEQSLLLEKAQAERLLRELADNRLTTVAEKSRVLQL EEELTLRRGEIEELQQCLLHSGPPPPDHPDAAEILRLRE RLLSASKEHQRESGVLRDKYEKALKAYQAEVDKLRAANE KYAQEVAGLKDKVQQATSENMGLMDNWKSKLDSLASDHQ KSLEDLKATLNSGPGAQQKEIGELKAVMEGIKMEHQLEL GNLQAKHDLETAMHVKEKEALREKLQEAQEELAGLQRHW RAQLEVQASQHRLELQEAQDQRRDAELRVHELEKLDVEY RGQAQAIEFLKEQISLAEKKMLDYERLQRAEAQGKQEVE SLREKLLVAENRLQAVEALCSSQHTHMIESNDISEETIR TKETVEGLQDKLNKRDKEVTALTSQTEMLRAQVSALESK CKSGEKKVDALLKEKRRLEAELETVSRKTHDASGQLVLI SQELLRKERSLNELRVLLLEANRHSPGPERDLSREVHKA EWRIKEQKLKDDIRGLREKLTGLDKEKSLSDQRRYSLID RSSAPELLRLQHQLMSTEDALRDA |
|
Database cross reference |
RefSeq Protein accession:NP_003379
|
Liver relevance
|
HLPP validation |
Yes/No |
Yes |
|
Project name |
Chinese Liver;French Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005875;C:microtubule associated complex;TAS:ProtInc. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr15754 |
PHOSPHORYLATION |
202 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
204 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
207 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
211 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
923 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
292 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
202 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
204 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
207 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
211 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
177 |
T |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
54 |
S |
PhosphoSitePlus |
LTP HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
294 |
S |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
352 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr15754 |
PHOSPHORYLATION |
923 |
S |
PhosphoSitePlus |
LTP |
N |
|
