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Protein basic information

LiverAtlas Protein ID

HuLPr16155

Uniprot ID

CP4X1_HUMAN

Uniprot Acc

Q8N118;

Protein name

Cytochrome P450 4X1

Comment

CATALYTIC ACTIVITY:RH + reduced flavoprotein + O(2) = ROH + oxidized flavoprotein + H(2)O.||COFACTOR:Heme group (By similarity).||SUBCELLULAR LOCATION:Endoplasmic reticulum membrane; Peripheral membrane protein (By similarity). Microsome membrane; Peripheral membrane protein (By similarity).||SIMILARITY:Belongs to the cytochrome P450 family.

Subcellular localization

Endoplasmic reticulum membrane;Peripheral membrane protein(By similarity).Microsome membrane;Peripheral membrane protein(By similarity).

Gene name

cytochrome P450, family 4, subfamily X, polypeptide 1

Protein sequence

MEFSWLETRWARPFYLAFVFCLALGLLQAIKLYLRRQRLL RDLRPFPAPPTHWFLGHQKFIQDDNMEKLEEIIEKYPRA FPFWIGPFQAFFCIYDPDYAKTLLSRTDPKSQYLQKFSP PLLGKGLAALDGPKWFQHRRLLTPGFHFNILKAYIEVMA HSVKMMLDKWEKICSTQDTSVEVYEHINSMSLDIIMKCA FSKETNCQTNSTHDPYAKAIFELSKIIFHRLYSLLYHSD IIFKLSPQGYRFQKLSRVLNQYTDTIIQERKKSLQAGVK QDNTPKRKYQDFLDIVLSAKDESGSSFSDIDVHSEVSTF LLAGHDTLAASISWILYCLALNPEHQERCREEVRGILGD GSSITWDQLGEMSYTTMCIKETCRLIPAVPSISRDLSKP LTFPDGCTLPAGITVVLSIWGLHHNPAVWKNPKVFDPLR FSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIA LILLHFRVTPDPTRPLTFPNHFILKPKNGMYLHLKKLSEC

Database cross reference

RefSeq Protein accession:NP_828847
RefSeq Protein gi:29837648

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005789;C:endoplasmic reticulum membrane;IEA:UniProtKB-SubCell. GO:0005792;C:microsome;IEA:UniProtKB-SubCell.

GO-F

GO:0070330;F:aromatase activity;IEA:EC. GO:0009055;F:electron carrier activity;IEA:InterPro. GO:0020037;F:heme binding;IEA:InterPro.

GO-P

GO:0055114;P:oxidation-reduction process;IEA:UniProtKB-KW.