Protein basic information
| LiverAtlas Protein ID |
HuLPr16293 |
|
Uniprot ID |
|
|
Uniprot Acc |
Q9H0B8;D3DUM0;Q6P590;Q6UWH0;Q6UXC6;Q96IB1;Q96K61; |
|
Protein name |
Cysteine-rich secretory protein LCCL domain-containing 2 |
|
Comment |
FUNCTION:Promotes matrix assembly (By similarity).||SUBUNIT:Binds to heparin, dermatan sulfate and chondroitin sulfate (By similarity).||SUBCELLULAR LOCATION:Secreted (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=5; Name=1; IsoId=Q9H0B8-1; Sequence=Displayed; Name=2; IsoId=Q9H0B8-2; Sequence=VSP 020183; Note=No experimental confirmation available; Name=3; IsoId=Q9H0B8-3; Sequence=VSP 020181, VSP 020182; Name=4; IsoId=Q9H0B8-4; Sequence=VSP 020178, VSP 020180; Note=No experimental confirmation available; Name=5; IsoId=Q9H0B8-5; Sequence=VSP 020179;||SIMILARITY:Belongs to the CRISP family.||SIMILARITY:Contains 2 LCCL domains. |
|
Subcellular localization |
Secreted(By similarity). |
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Gene name |
|
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Protein sequence
|
MSCVLGGVIPLGLLFLVCGSQGYLLPNVTLLEELLSKYQH NESHSRVRRAIPREDKEEILMLHNKLRGQVQPQASNMEY MTWDDELEKSAAAWASQCIWEHGPTSLLVSIGQNLGAHW GRYRSPGFHVQSWYDEVKDYTYPYPSECNPWCPERCSGP MCTHYTQIVWATTNKIGCAVNTCRKMTVWGEVWENAVYF VCNYSPKGNWIGEAPYKNGRPCSECPPSYGGSCRNNLCY REETYTPKPETDEMNEVETAPIPEENHVWLQPRVMRPTK PKKTSAVNYMTQVVRCDTKMKDRCKGSTCNRYQCPAGCL NHKAKIFGTLFYESSSSICRAAIHYGILDDKGGLVDITR NGKVPFFVKSERHGVQSLSKYKPSSSFMVSKVKVQDLDC YTTVAQLCPFEKPATHCPRIHCPAHCKDEPSYWAPVFGT NIYADTSSICKTAVHAGVISNESGGDVDVMPVDKKKTYV GSLRNGVQSESLGTPRDGKAFRIFAVRQ |
|
Database cross reference |
RefSeq Protein accession:NP_113664
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Liver relevance
|
HLPP validation |
Yes/No |
Yes |
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Project name |
Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0005576;C:extracellular region;IEA:UniProtKB-SubCell. GO:0030133;C:transport vesicle;IDA:LIFEdb. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr16293 |
PHOSPHORYLATION |
285 |
T |
PhosphoSitePlus |
LTP |
N |
 
|
|
|
HuLPr16293 |
PHOSPHORYLATION |
292 |
T |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr16293 |
PHOSPHORYLATION |
283 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr16293 |
PHOSPHORYLATION |
369 |
S |
PhosphoSitePlus |
LTP |
N |
|
