Choose one of the five choices you want to search:

Gene, Transcriptome, Protein, Pathway or Disease. 

Protein basic information

LiverAtlas Protein ID

HuLPr16474

Uniprot ID

CTHR1_HUMAN

Uniprot Acc

Q96CG8;Q6UW91;Q8IX63;

Protein name

Collagen triple helix repeat-containing protein 1

Comment

FUNCTION:May act as a negative regulator of collagen matrix deposition (By similarity).||SUBCELLULAR LOCATION:Secreted, extracellular space, extracellular matrix (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q96CG8-1; Sequence=Displayed; Name=2; IsoId=Q96CG8-2; Sequence=VSP 013622, VSP 013623; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Isoform 1 is expressed in calcified atherosclerotic plaque and chondrocyte-like cells.||PTM:N-glycosylated (By similarity).||SIMILARITY:Contains 1 collagen-like domain.||WEB RESOURCE:Name=Atlas of Genetics and Cytogenetics in Oncology and Haematology; URL="http://atlasgeneticsoncology.org/Genes/CTHRC1ID40193ch8q22.html";

Subcellular localization

Secreted, extracellular space, extracellular matrix(By similarity).

Gene name

collagen triple helix repeat containing 1

Protein sequence

MRPQGPAASPQRLRGLLLLLLLQLPAPSSASEIPKGKQKA QLRQREVVDLYNGMCLQGPAGVPGRDGSPGANGIPGTPG IPGRDGFKGEKGECLRESFEESWTPNYKQCSWSSLNYGI DLGKIAECTFTKMRSNSALRVLFSGSLRLKCRNACCQRW YFTFNGAECSGPLPIEAIIYLDQGSPEMNSTINIHRTSS VEGLCEGIGAGLVDVAIWVGTCSDYPKGDASTGWNSVSR IIIEELPK

Database cross reference

RefSeq Protein accession:NP_612464
RefSeq Protein gi:19923989

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005581;C:collagen;IEA:UniProtKB-KW.

Pathway

Pathway name

Noncanonical_Wnt_signaling_pathway

Pathway name

Wnt_signaling_network