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Protein basic information

LiverAtlas Protein ID

HuLPr17093

Uniprot ID

D3DRD5_HUMAN

Uniprot Acc

D3DRD5;

Protein name

Fibroblast growth factor receptor 2 (Bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1,

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SIMILARITY:Contains 1 protein kinase domain.

Gene name

fibroblast growth factor receptor 2

Protein sequence

MGLTSTWRYGRGPGIGTVTMVSWGRFICLVVVTMATLSLA RPSFSLVEDTTLEPEEPPTKYQISQPEVYVAAPGESLEV RCLLKDAAVISWTKDGVHLGPNNRTVLIGEYLQIKGATP RDSGLYACTASRTVDSETWYFMVNVTDAISSGDDEDDTD GAEDFVSENSNNKRAPYWTNTEKMEKRLHAVPAANTVKF RCPAGGNPMPTMRWLKNGKEFKQEHRIGGYKVRNQHWSL IMESVVPSDKGNYTCVVENEYGSINHTYHLDVVERSPHR PILQAGLPANASTVVGGDVEFVCKVYSDAQPHIQWIKHV EKNGSKYGPDGLPYLKVLKAAGVNTTDKEIEVLYIRNVT FEDAGEYTCLAGNSIGISFHSAWLTVLPAPGREKEITAS PDYLEIAIYCIGVFLIACMVVTVILCRMKNTTKKPDFSS QPAVHKLTKRIPLRRQVSAESSSSMNSNTPLVRITTRLS STADTPMLAGVSEYELPEDPKWEFPRDKLTLGKPLGEGC FGQVVMAEAVGIDKDKPKEAVTVAVKMLKDDATEKDLSD LVSEMEMMKMIGKHKNIINLLGACTQDGPLYVIVEYASK GNLREYLRARRPPGMEYSYDINRVPEEQMTFKDLVSCTY QLARGMEYLASQKCIHRDLAARNVLVTENNVMKIADFGL ARDINNIDYYKKTTNGRLPVKWMAPEALFDRVYTHQSDV WSFGVLMWEIFTLGGSPYPGIPVEELFKLLKEGHRMDKP ANCTNELYMMMRDCWHAVPSQRPTFKQLVEDLDRILTLT TNEEYLDLSQPLEQYSPSYPDTRSSCSSGDDSVFSPDPMPYEPCLPQYPHINGSVKT

Database cross reference

RefSeq Protein accession:NP_000132
RefSeq Protein gi:221316639

Liver relevance

HLPP validation

Yes/No

Yes

Project name

French Liver;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0005007;F:fibroblast growth factor receptor activity;IEA:InterPro.

GO-P

GO:0008284;P:positive regulation of cell proliferation;IEA:InterPro.