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Protein basic information

LiverAtlas Protein ID

HuLPr17164

Uniprot ID

D3DTH3_HUMAN

Uniprot Acc

D3DTH3;

Protein name

Active BCR-related

Comment

SIMILARITY:Contains 1 C2 domain.||SIMILARITY:Contains 1 DH (DBL-homology) domain.||SIMILARITY:Contains 1 PH domain.||SIMILARITY:Contains 1 Rho-GAP domain.

Gene name

active BCR-related gene

Protein sequence

MEPLSHRGLPRLSWIDTLYSNFSYGTDEYDGEGNEEQKGP PEGSETMPYIDESPTMSPQLSARSQGGGDGVSPTPPEGL APGVEAGKGLEMRKLVLSGFLASEEIYINQLEALLLPMK PLKATATTSQPVLTIQQIETIFYKIQDIYEIHKEFYDNL CPKVQQWDSQVTMGHLFQKLASQLGVYKAFVDNYKVALE TAEKCSQSNNQFQKISEELKVKGPKDSKDSHTSVTMEAL LYKPIDRVTRSTLVLHDLLKHTPVDHPDYPLLQDALRIS QNFLSSINEDIDPRRTAVTTPKGETRQLVKDGFLVEVSE SSRKLRHVFLFTDVLLCAKLKKTSAGKHQQYDCKWYIPL ADLVFPSPEESEASPQVHPFPDHELEDMKMKISALKSEI QKEKANKGQSRAIERLKKKMFENEFLLLLNSPTIPFRIH NRNGKSYLFLLSSDYERSEWREAIQKLQKKDLQAFVLSS VELQVLTGSCFKLRTVHNIPVTSNKDDDESPGLYGFLHV IVHSAKGFKQSANLYCTLEVDSFGYFVSKAKTRVFRDTA EPKWDEEFEIELEGSQSLRILCYEKCYDKTKVNKDNNEI VDKIMGKGQIQLDPQTVETKNWHTDVIEMNGIKVEFSMK FTSRDMSLKRTPSKKQTGVFGVKISVVTKRERSKVPYIV RQCVEEVEKRGIEEVGIYRISGVATDIQALKAVFDANNK DILLMLSDMDINAIAGTLKLYFRELPEPLLTDRLYPAFM EGIALSDPAAKENCMMHLLRSLPDPNLITFLFLLEHLKR VAEKEPINKMSLHNLATVFGPTLLRPSEVESKAHLTSAA DIWSHDVMAQVQVLLYYLQHPPISFAELKRNTLYFSTDV

Database cross reference

RefSeq Protein accession:NP_001083
RefSeq Protein gi:38679954

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005622;C:intracellular;IEA:InterPro.

GO-F

GO:0005096;F:GTPase activator activity;IEA:UniProtKB-KW. GO:0005089;F:Rho guanyl-nucleotide exchange factor activity;IEA:InterPro.

GO-P

GO:0035556;P:intracellular signal transduction;IEA:InterPro. GO:0035023;P:regulation of Rho protein signal transduction;IEA:InterPro.