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Protein basic information

LiverAtlas Protein ID

HuLPr18306

Uniprot ID

DEFB1_HUMAN

Uniprot Acc

P60022;Q09753;

Protein name

Beta-defensin 1

Comment

FUNCTION:Has bactericidal activity (By similarity).||SUBCELLULAR LOCATION:Secreted.||TISSUE SPECIFICITY:Plasma.||MASS SPECTROMETRY:Mass=3928; Mass error=0.5; Method=Electrospray; Range=33-68; Source=PubMed:7628632;||SIMILARITY:Belongs to the beta-defensin family.

Subcellular localization

Secreted.

Gene name

defensin, beta 1

Protein sequence

MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSS GGQCLYSACPIFTKIQGTCYRGKAKCCK

Database cross reference

RefSeq Protein accession:NP_005209
RefSeq Protein gi:4885181

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

Ontology annotation

GO-C

GO:0005576;C:extracellular region;IEA:UniProtKB-SubCell.

GO-P

GO:0006935;P:chemotaxis;TAS:ProtInc. GO:0042742;P:defense response to bacterium;IEA:UniProtKB-KW. GO:0007186;P:G-protein coupled receptor protein signaling pathway;TAS:ProtInc. GO:0045087;P:innate immune response;ISS:UniProtKB.