Protein basic information
| LiverAtlas Protein ID |
HuLPr18481 |
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Uniprot ID |
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Uniprot Acc |
P80370;P15803;Q96DW5; |
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Protein name |
Protein delta homolog 1 |
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Comment |
FUNCTION:May have a role in neuroendocrine differentiation.||SUBUNIT:Monomer.||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Comment=Additional isoforms seem to exist; Name=Long; IsoId=P80370-1; Sequence=Displayed; Name=Short; IsoId=P80370-2; Sequence=VSP 001377;||TISSUE SPECIFICITY:Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendocrine lung tumor tissue.||PTM:N- and O-glycosylated.||SIMILARITY:Contains 6 EGF-like domains.||SEQUENCE CAUTION:Sequence=CAA35582.1; Type=Frameshift; Positions=22, 108, 199; |
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Subcellular localization |
Membrane;Single-pass type I membrane protein. |
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Gene name |
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Protein sequence
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MTATEALLRVLLLLLAFGHSTYGAECFPACNPQNGFCEDD NVCRCQPGWQGPLCDQCVTSPGCLHGLCGEPGQCICTDG WDGELCDRDVRACSSAPCANNRTCVSLDDGLYECSCAPG YSGKDCQKKDGPCVINGSPCQHGGTCVDDEGRASHASCL CPPGFSGNFCEIVANSCTPNPCENDGVCTDIGGDFRCRC PAGFIDKTCSRPVTNCASSPCQNGGTCLQHTQVSYECLC KPEFTGLTCVKKRALSPQQVTRLPSGYGLAYRLTPGVHE LPVQQPEHRILKVSMKELNKKTPLLTEGQAICFTILGVL TSLVVLGTVGIVFLNKCETWVSNLRYNHMLRKKKNLLLQ YNSGEDLAVNIIFPEKIDMTTFSKEAGDEEI |
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Database cross reference |
RefSeq Protein accession:NP_003827
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver; |
Ontology annotation
| GO-C |
GO:0005615;C:extracellular space;TAS:ProtInc. GO:0016021;C:integral to membrane;TAS:ProtInc. GO:0005625;C:soluble fraction;TAS:ProtInc. |
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GO-P |
GO:0007275;P:multicellular organismal development;TAS:ProtInc. |
Pathway
| Pathway name | |
| Pathway name |
