Protein basic information
| LiverAtlas Protein ID |
HuLPr18588 |
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Uniprot ID |
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Uniprot Acc |
Q9Y3R5;D3DSG5;Q6PJQ7;Q9UEZ3; |
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Protein name |
Protein dopey-2 |
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Comment |
FUNCTION:May be involved in protein traffic between late Golgi and early endosomes (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9Y3R5-1; Sequence=Displayed; Name=2; IsoId=Q9Y3R5-2; Sequence=VSP 027387; Note=No experimental confirmation available;||TISSUE SPECIFICITY:Ubiquitously expressed. Overexpressed in lymphoblasts from Down syndrome patients.||DEVELOPMENTAL STAGE:Abundantly expressed in developing central nervous system, with highest levels in cerebellum and lowest in telencephalon.||SIMILARITY:Belongs to the dopey family. |
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Gene name |
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Protein sequence
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MDPEEQELLNDYRYRSYSSVIEKALRNFESSSEWADLISS LGKLNKALQSNLRYSLLPRRLLISKRLAQCLHPALPSGV HLKALETYEIIFKIVGTKWLAKDLFLYSCGLFPLLAHAA VSVRPVLLTLYEKYFLPLQKLLLPSLQAFIVGLLPGLEE GSEISDRTDALLLRLSLVVGKEVFYTALWGSVLASPSIR LPASVFVVGHINRDAPGREQKYMLGTNHQLTVKSLRASL LDSNVLVQRNNLEIVLFFFPFYTCLDSNERAIPLLRSDI VRILSAATQTLLRRDMSLNRRLYAWLLGSDIKGNTVVPE SEISNSYEDQSSYFFEKYSKDLLVEGLAEILHQKFIDAD VEERHHAYLKPFRVLISLLDKPEIGPQVVGNLFLEVIRA FYSYCRDALGSDLKLSYTQSGNSLISAIKENRNASEIVK TVNLLITSLSTDFLWDYMTRCFEECFRPVKQRYSVRNSV SPPPTVSELCALLVFLLDVIPLELYSEVQTQYLPQVLGC LVQPLAEDMEALSLPELTHALKTCFKVLSKVQMPPSYLD TESTSGTSSPVKGENGKIILETKAVIPGDEDASFPPLKS EDSGIGLSASSPELSEHLRVPRVSLERDDVWKKGGSMQR TFLCIQELIANFASKNIFGVQLTASGEESKSEEPAGKRD RDGTQSLAANDSSRKNSWEPKPITVPQFKQMLSDLFTAR GSPFKTKSSESPSSSPSSPARKNGGEWDVEKVVIDLGGS REERREAFAAACHLLLDCATFPVYLSEEETEQLCATLFQ LPGAGDSSFPSWLKSLMTICCCVTDCYLQNVAISTLLEV INHSQSLALVIEDKMKRYKSSGHNPFFGKLQMVTVPPIA PGILKVIAEKTDFYQRVARVLWNQLNKETREHHVTCVEL FYRLHCLAPTANICEDIICHALLDPDKGTRLEALFRFSV IWHLTREIQGSRVTSHNRSFDRSLFVVLDSLACTDGAIG AAAQGWLVRALSLGDVARILEPVL |
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Database cross reference |
RefSeq Protein accession:NP_005119
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver;French Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0000139;C:Golgi membrane;ISS:HGNC. |
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GO-P |
GO:0007029;P:endoplasmic reticulum organization;ISS:HGNC. GO:0006895;P:Golgi to endosome transport;ISS:HGNC. GO:0007275;P:multicellular organismal development;NAS:UniProtKB. GO:0015031;P:protein transport;IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
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HuLPr18588 |
PHOSPHORYLATION |
936 |
S |
PhosphoSitePlus |
LTP |
N |
 
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