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Protein basic information

LiverAtlas Protein ID

HuLPr19330

Uniprot ID

E5KTA5_HUMAN

Uniprot Acc

E5KTA5;

Protein name

Uracil-DNA glycosylase

Comment

FUNCTION:Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity).||SIMILARITY:Belongs to the uracil-DNA glycosylase family.

Gene name

uracil-DNA glycosylase

Protein sequence

MIGQKTLYSFFSPSPARKRHAPSPEPAVQGTGVAGVPEES GDAAAIPAKKAPAGQEEPGTPPSSPLSAEQLDRIQRNKA AALLRLAARNVPVGFGESWKKHLSGEFGKPYFIKLMGFV AEERKHYTVYPPPHQVFTWTQMCDIKDVKVVILGQDPYH GPNQAHGLCFSVQRPVPPPPSLENIYKELSTDIEDFVHP GHGDLSGWAKQGVLLLNAVLTVRAHQANSHKERGWEQFT DAVVSWLNQNSNGLVFLLWGSYAQKKGSAIDRKRHHVLQ TAHPSPLSVYRGFFGCRHFSKTNELLQKSGKKPIDWKEL

Database cross reference

RefSeq Protein accession:NP_003353
RefSeq Protein gi:6224979

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0004844;F:uracil DNA N-glycosylase activity;IEA:HAMAP.

GO-P

GO:0006284;P:base-excision repair;IEA:HAMAP.