HuLPr19401

Uniprot ID

E7BSV0_HUMAN

Uniprot Acc

E7BSV0;

Protein name

Epidermal growth factor receptor variant A

Comment

CATALYTIC ACTIVITY:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate.||SIMILARITY:Belongs to the protein kinase superfamily. Tyr protein kinase family.||SIMILARITY:Contains 1 protein kinase domain.

Gene name

epidermal growth factor receptor

Protein sequence

MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQ LGTFEDHFLSLQRMFNNCEVVLGNLEITYVQRNYDLSFL KTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYA LAVLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALC NVESIQWRDIVSSDFLSNMSMDFQNHLGSCQKCDPSCPN GSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQ CAAGCTGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTT YQMDVNPEGKYSFGATCVKKCPRNYVVTDHGSCVRACGA DSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSIN ATNIKHFKNCTSISGDLHILPVAFRGDSFTHTPPLDPQE LDILKTVKEITGFLLIQAWPENRTDLHAFENLEIIRGRT KQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNL CYANTINWKKLFGTSGQKTKIISNRGENSCKATGQVCHA LCSPEGCWGPEPRDCVSCRNVSRGRECVDKCNLLEGEPR EFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYI DGPHCVKTCPAGVMGENNTLVWKYADAGHVCHLCHPNCT YGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVVALGI GLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQAL LRILKETEFKKIKVLGSGAFGTVYKGLWIPEGEKVKIPV AIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGIC LTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQ IAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLA KLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVW SYGVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPP ICTIDVYMIMVKCWMIDADSRPKFRELIIEFSKMARDPQ RYLVIQGDERMHLPSPTDSNFYRA

Database cross reference

RefSeq Protein accession:NP_005219
RefSeq Protein gi:29725609

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Fetal Liver;Human Liver Organelles;

GO:0016021;C:integral to membrane;IEA:InterPro.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0004716;F:receptor signaling protein tyrosine kinase activity;IEA:InterPro. GO:0004714;F:transmembrane receptor protein tyrosine kinase activity;IEA:InterPro.

GO-P

GO:0007169;P:transmembrane receptor protein tyrosine kinase signaling pathway;IEA:InterPro.