HuLPr19903

Uniprot ID

E7EVW0_HUMAN

Uniprot Acc

E7EVW0;

Protein name

DNA polymerase

Comment

CATALYTIC ACTIVITY:Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).||SIMILARITY:Belongs to the DNA polymerase type-B family.||CAUTION:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.

Gene name

polymerase (DNA directed), delta 1, catalytic subunit 125kDa

Protein sequence

MDGKRRPGPGPGVPPKRARGGLWDDDDAPRPSQFEEDLAL MEEMEAEHRLQEQEEEELQSVLEGVADGQVPPSAIDPRW LRPTPPALDPQTEPLIFQQLEIDHYVGPAQPVPGGPPPS RGSVPVLRAFGVTDEGFSVCCHIHGFAPYFYTPAPPGFG PEHMGDLQRELNLAISRDSRGGRELTGPAVLAVELCSRE SMFGYHGHGPSPFLRITVALPRLVAPARRLLEQGIRVAG LGTPSFAPYEANVDFEIRFMVDTDIVGCNWLELPAGKYA LRLKEKATQCQLEADVLWSDVVSHPPEGPWQRIAPLRVL SFDIECAGRKGIFPEPERDPVIQICSLGLRWGEPEPFLR LALTLRPCAPILGAKVQSYEKEEDLLQAWSTFIRIMDPD VITGYNIQNFDLPYLISRAQTLKVQTFPFLGRVAGLCSN IRDSSFQSKQTGRRDTKVVSMVGRVQMDMLQVLLREYKL RSYTLNAVSFHFLGEQKEDVQHSIITDLQNGNDQTRRRL AVYCLKDAYLPLRLLERLMVLVNAVEMARVTGVPLSYLL SRGQQVKVVSQLLRQAMHEGLLMPVVKSEGGEDYTGATV IEPLKGVRPQDRAGAAWELLALTPGRGCSPPRYYDVPIA TLDFSSLYPSIMMAHNLCYTTLLRPGTAQKLGLTEDQFI RTPTGDEFVKTSVRKGLLPQILENLLSARKRAKAELAKE TDPLRRQVLDGRQLALKVSANSVYGFTGAQVGKLPCLEI SQSVTGFGRQMIEKTKQLVESKYTVENGYSTSAKVVYGD TDSVMCRFGVSSVAEAMALGREAADWVSGHFPSPIRLEF EKVYFPYLLISKKRYAGLLFSSRPDAHDRMDCKGLEAVR RDNCPLVANLVTASLRRLLIDRDPEGAVAHAQDVISDLL CNRIDISQLVITKELTRAASDYAGKQAHVELAERMRKRD PGSAPSLGDRVPYVIISAAKGVAAYMKSEDPLFVLEHSL PIDTQYYLEQQLAKPLLRIFEPIL

Database cross reference

RefSeq Protein accession:NP_002682
RefSeq Protein gi:156616275

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;

GO-F

GO:0003677;F:DNA binding;IEA:UniProtKB-KW. GO:0003887;F:DNA-directed DNA polymerase activity;IEA:UniProtKB-KW. GO:0000166;F:nucleotide binding;IEA:InterPro.

GO-P

GO:0006260;P:DNA replication;IEA:UniProtKB-KW.