Protein basic information
| LiverAtlas Protein ID |
HuLPr23350 |
|
Uniprot ID |
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Uniprot Acc |
Q96P31;A0N0M4;A8MTH7;D3DVD2;Q5VXZ8;Q8N6S2;Q96LA4;Q96P27;Q96P28;Q96P29;Q96P30; |
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Protein name |
Fc receptor-like protein 3 |
|
Comment |
SUBUNIT:Interacts with PTPN6, PTPN11, SYK and ZAP70.||SUBCELLULAR LOCATION:Cell membrane; Single-pass type I membrane protein.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=7; Name=1; Synonyms=Spap2a; IsoId=Q96P31-1; Sequence=Displayed; Name=2; Synonyms=Spap2b; IsoId=Q96P31-2; Sequence=VSP 033300; Name=3; Synonyms=Spap2c; IsoId=Q96P31-3; Sequence=VSP 033305; Name=4; Synonyms=Spap2d; IsoId=Q96P31-4; Sequence=VSP 033301, VSP 033303; Name=5; IsoId=Q96P31-5; Sequence=VSP 033302, VSP 033304; Name=6; IsoId=Q96P31-6; Sequence=VSP 033308; Note=No experimental confirmation available; Name=7; IsoId=Q96P31-7; Sequence=VSP 033306, VSP 033307;||TISSUE SPECIFICITY:Primarily expressed in secondary lymphoid tissues by mature subsets of B cells. Detected in spleen, lymph node, peripheral blood lymphocytes, thymus, bone marrow, kidney, salivary gland, adrenal gland and uterus. Expressed a low levels in naive, germinal center and memory B cells but also expressed in NK |
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Subcellular localization |
Cell membrane;Single-pass type I membrane protein. |
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Gene name |
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Protein sequence
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MLLWLLLLILTPGREQSGVAPKAVLLLNPPWSTAFKGEKV ALICSSISHSLAQGDTYWYHDEKLLKIKHDKIQITEPGN YQCKTRGSSLSDAVHVEFSPDWLILQALHPVFEGDNVIL RCQGKDNKNTHQKVYYKDGKQLPNSYNLEKITVNSVSRD NSKYHCTAYRKFYILDIEVTSKPLNIQVQELFLHPVLRA SSSTPIEGSPMTLTCETQLSPQRPDVQLQFSLFRDSQTL GLGWSRSPRLQIPAMWTEDSGSYWCEVETVTHSIKKRSL RSQIRVQRVPVSNVNLEIRPTGGQLIEGENMVLICSVAQ GSGTVTFSWHKEGRVRSLGRKTQRSLLAELHVLTVKESD AGRYYCAADNVHSPILSTWIRVTVRIPVSHPVLTFRAPR AHTVVGDLLELHCESLRGSPPILYRFYHEDVTLGNSSAP SGGGASFNLSLTAEHSGNYSCDADNGLGAQHSHGVSLRV TVPVSRPVLTLRAPGAQAVVGDLLELHCESLRGSFPILY WFYHEDDTLGNISAHSGGGASFNLSLTTEHSGNYSCEAD NGLGAQHSKVVTLNVTGTSRNRTGLTAAGITGLVLSILV LAAAAALLHYARARRKPGGLSATGTSSHSPSECQEPSSS RPSRIDPQEPTHSKPLAPMELEPMYSNVNPGDSNPIYSQ IWSIQHTKENSANCPMMHQEHEELTVLYSELKKTHPDDS AGEASSRGRAHEEDDEENYENVPRVLLASDH |
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Database cross reference |
RefSeq Protein accession:NP_443171
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005886;C:plasma membrane;IEA:UniProtKB-SubCell. |
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GO-F |
GO:0004872;F:receptor activity;IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr23350 |
PHOSPHORYLATION |
722 |
Y |
PhosphoSitePlus |
LTP |
N |
 
|
|
|
HuLPr23350 |
PHOSPHORYLATION |
161 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr23350 |
PHOSPHORYLATION |
166 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr23350 |
PHOSPHORYLATION |
650 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr23350 |
PHOSPHORYLATION |
662 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr23350 |
PHOSPHORYLATION |
692 |
Y |
PhosphoSitePlus |
LTP |
N |
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