HuLPr23352

Uniprot ID

FCRL5_HUMAN

Uniprot Acc

Q96RD9;A0N0M2;B7WNT9;B7WP94;Q495Q2;Q495Q4;Q5VYK9;Q6UY46;

Protein name

Fc receptor-like protein 5

Comment

FUNCTION:May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells.||SUBCELLULAR LOCATION:Cell membrane; Single-pass type I membrane protein.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=5; Name=1; Synonyms=IRTA2c; IsoId=Q96RD9-1; Sequence=Displayed; Name=2; IsoId=Q96RD9-2; Sequence=VSP 017379, VSP 017380; Name=3; Synonyms=IRTA2a; IsoId=Q96RD9-3; Sequence=VSP 017385, VSP 017386; Name=4; Synonyms=IRTA2b; IsoId=Q96RD9-4; Sequence=VSP 017383, VSP 017384; Name=5; Synonyms=IRTA2d; IsoId=Q96RD9-5; Sequence=VSP 017381, VSP 017382;||TISSUE SPECIFICITY:Expressed in marginal zone B-cells, immunoblasts, tonsillar germinal center centrocytes and in the intraepithelial and interfollicular regions of the tonsil. Expressed in many lymphoma cell lines and on hairy cell leukemia cells. Isoform 1, isoform 3, isoform 4 and isoform 5 are detecte

Subcellular localization

Cell membrane;Single-pass type I membrane protein.

Gene name

Fc receptor-like 5

Protein sequence

MLLWVILLVLAPVSGQFARTPRPIIFLQPPWTTVFQGERV TLTCKGFRFYSPQKTKWYHRYLGKEILRETPDNILEVQE SGEYRCQAQGSPLSSPVHLDFSSASLILQAPLSVFEGDS VVLRCRAKAEVTLNNTIYKNDNVLAFLNKRTDFHIPHAC LKDNGAYRCTGYKESCCPVSSNTVKIQVQEPFTRPVLRA SSFQPISGNPVTLTCETQLSLERSDVPLRFRFFRDDQTL GLGWSLSPNFQITAMWSKDSGFYWCKAATMPYSVISDSP RSWIQVQIPASHPVLTLSPEKALNFEGTKVTLHCETQED SLRTLYRFYHEGVPLRHKSVRCERGASISFSLTTENSGN YYCTADNGLGAKPSKAVSLSVTVPVSHPVLNLSSPEDLI FEGAKVTLHCEAQRGSLPILYQFHHEGAALERRSANSAG GVAISFSLTAEHSGNYYCTADNGFGPQRSKAVSLSVTVP VSHPVLTLSSAEALTFEGATVTLHCEVQRGSPQILYQFY HEDMPLWSSSTPSVGRVSFSFSLTEGHSGNYYCTADNGF GPQRSEVVSLFVTVPVSRPILTLRVPRAQAVVGDLLELH CEAPRGSPPILYWFYHEDVTLGSSSAPSGGEASFNLSLT AEHSGNYSCEANNGLVAQHSDTISLSVIVPVSRPILTFR APRAQAVVGDLLELHCEALRGSSPILYWFYHEDVTLGKI SAPSGGGASFNLSLTTEHSGIYSCEADNGLEAQRSEMVT LKVAVPVSRPVLTLRAPGTHAAVGDLLELHCEALRGSPL ILYRFFHEDVTLGNRSSPSGGASLNLSLTAEHSGNYSCE ADNGLGAQRSETVTLYITGLTANRSGPFATGVAGGLLSI AGLAAGALLLYCWLSRKAGRKPASDPARSPSDSDSQEPT YHNVPAWEELQPVYTNANPRGENVVYSEVRIIQEKKKHA VASDPRHLRNKGSPIIYSEVKVASTPVSGSLFLASSAPHR

Database cross reference

RefSeq Protein accession:NP_001182317
RefSeq Protein gi:306035194

HLPP validation

Yes/No

Yes

Project name

French Liver;Human Liver Organelles;

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005886;C:plasma membrane;IEA:UniProtKB-SubCell.

GO-F

GO:0004872;F:receptor activity;IEA:UniProtKB-KW.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr23352

PHOSPHORYLATION

850

T

PhosphoSitePlus

2526739

LTP

N