HuLPr23354

Uniprot ID

FCRLA_HUMAN

Uniprot Acc

Q7L513;A0N0M1;Q5VXA1;Q5VXA2;Q5VXA3;Q5VXA4;Q5VXB0;Q8NEW4;Q8WXH3;Q96PC6;Q96PJ0;Q96PJ1;Q96PJ2;Q96PJ4;Q9BR57;

Protein name

Fc receptor-like A

Comment

FUNCTION:May be implicated in B-cell differentiation and lymphomagenesis.||SUBUNIT:Monomer or homodimer; disulfide-linked.||SUBCELLULAR LOCATION:Secreted (Probable). Cytoplasm.||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=9; Name=1; Synonyms=FCRLa; IsoId=Q7L513-1; Sequence=Displayed; Name=2; Synonyms=FCRLa1; IsoId=Q7L513-2; Sequence=VSP 017605; Name=3; Synonyms=FCRLb; IsoId=Q7L513-3; Sequence=VSP 017608; Name=4; Synonyms=FCRLc1; IsoId=Q7L513-4; Sequence=VSP 017606; Name=5; Synonyms=FCRLc2; IsoId=Q7L513-5; Sequence=VSP 017604; Name=6; Synonyms=FCRLd; IsoId=Q7L513-6; Sequence=VSP 017607; Name=7; Synonyms=FCRLe; IsoId=Q7L513-7; Sequence=VSP 017603; Name=8; Synonyms=FCRLf; IsoId=Q7L513-8; Sequence=VSP 017609; Name=9; IsoId=Q7L513-9; Sequence=VSP 038297;||TISSUE SPECIFICITY:Expressed specifically in primary and secondary lymphoid tissues like lymph node, spleen and tonsil. Specifically expressed in B-cells with a high level in normal germinal center B-c

Subcellular localization

Secreted(Probable).Cytoplasm.

Gene name

Fc receptor-like A

Protein sequence

MKLGCVLMAWALYLSLGVLWVAQMLLAASFETLQCEGPVC TEESSCHTEDDLTDAREAGFQVKAYTFSEPFHLIVSYDW LILQGPAKPVFEGDLLVLRCQAWQDWPLTQVTFYRDGSA LGPPGPNREFSITVVQKADSGHYHCSGIFQSPGPGIPET ASVVAITVQELFPAPILRAVPSAEPQAGSPMTLSCQTKL PLQRSAARLLFSFYKDGRIVQSRGLSSEFQIPTASEDHS GSYWCEAATEDNQVWKQSPQLEIRVQGASSSAAPPTLNP APQKSAAPGTAPEEAPGPLPPPPTPSSEDPGFSSPLGMP DPHLYHQMGLLLKHMQDVRVLLGHLLMELRELSGHRKPGTTKATAE

Database cross reference

RefSeq Protein accession:NP_001171795
RefSeq Protein gi:296434253

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

GO:0005737;C:cytoplasm;IDA:MGI. GO:0005576;C:extracellular region;IEA:UniProtKB-SubCell.

GO-P

GO:0030154;P:cell differentiation;IEA:UniProtKB-KW.