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Protein basic information

LiverAtlas Protein ID

HuLPr23831

Uniprot ID

GBP6_HUMAN

Uniprot Acc

Q6ZN66;A2RRM3;Q6ZN86;Q7Z3F0;

Protein name

Guanylate-binding protein 6

Comment

FUNCTION:Binds GTP, GDP and GMP (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q6ZN66-1; Sequence=Displayed; Name=2; IsoId=Q6ZN66-2; Sequence=VSP 030155;||SIMILARITY:Belongs to the GBP family.

Gene name

guanylate binding protein family, member 6

Protein sequence

MESGPKMLAPVCLVENNNEQLLVNQQAIQILEKISQPVVV VAIVGLYRTGKSYLMNHLAGQNHGFPLGSTVQSETKGIW MWCVPHPSKPNHTLVLLDTEGLGDVEKGDPKNDSWIFAL AVLLCSTFVYNSMSTINHQALEQLHYVTELTELIKAKSS PRPDGVEDSTEFVSFFPDFLWTVRDFTLELKLNGHPITE DEYLENALKLIQGNNPRVQTSNFPRECIRRFFPKRKCFV FDRPTNDKDLLANIEKVSEKQLDPKFQEQTNIFCSYIFT HARTKTLREGITVTGNRLGTLAVTYVEAINSGAVPCLEN AVITLAQRENSAAVQRAADYYSQQMAQRVKLPTDTLQEL LDMHAACEREAIAIFMEHSFKDENQEFQKKFMETTMNKK GDFLLQNEESSVQYCQAKLNELSKGLMESISAGSFSVPG GHKLYMETKERIEQDYWQVPRKGVKAKEVFQRFLESQMV IEESILQSDKALTDREKAVAVDRAKKEAAEKEQELLKQK LQEQQQQMEAQDKSRKENIAQLKEKLQMEREHLLREQIM MLEHTQKVQNDWLHEGFKKKYEEMNAEISQFKRMIDTTK NDDTPWIARTLDNLADELTAILSAPAKLIGHGVKGVSSLFKKHKLPF

Database cross reference

RefSeq Protein accession:NP_940862
RefSeq Protein gi:157671915

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-F

GO:0005525;F:GTP binding;IEA:UniProtKB-KW. GO:0003924;F:GTPase activity;IEA:InterPro.