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Protein basic information

LiverAtlas Protein ID

HuLPr23984

Uniprot ID

GIMA8_HUMAN

Uniprot Acc

Q8ND71;

Protein name

GTPase IMAP family member 8

Comment

FUNCTION:Exerts an anti-apoptotic effect in the immune system and is involved in responses to infections (By similarity).||SUBCELLULAR LOCATION:Endoplasmic reticulum (By similarity). Golgi apparatus (By similarity). Mitochondrion (By similarity).||SIMILARITY:Belongs to the IAN GTP-binding protein family.

Subcellular localization

Endoplasmic reticulum(By similarity).Golgi apparatus(By similarity).Mitochondrion(By similarity).

Gene name

GTPase, IMAP family member 8

Protein sequence

MSEQSCQMSELRLLLLGKCRSGKSATGNAILGKHVFKSKF SDQTVIKMCQRESWVLRERKVVVIDTPDLFSSIACAEDK QRNIQHCLELSAPSLHALLLVIAIGHFTREDEETAKGIQ QVFGAEARRHIIIVFTRKDDLGDDLLQDFIEKNKPLKQL VQDYEGRYCIFNNKTNSKDEQITQVLELLRKVESLVNTN GGPYHVNFKTEGSRFQDCVNEAASQEGDKPQGPRERQLQ STGPEQNPGTSELTVLLVGKRGAGKSAAGNSILGRQAFQ TGFSEQSVTQSFLSESRSWRKKKVSIIDAPDISSLKNID SEVRKHICTGPHAFLLVTPLGFYTKNDEAVLSTIQNNFG EKFFEYMIILLTRKEDLGDQDLDTFLRNSNKALYGLIQK CKNRYSAFNYRATGEEEQRQADELLEKIESMVHQNGNKH CVFREKETLNIVLVGRSGTGKSATGNSILGSLVFTSRLR AQPVTKTSQSGRRTWDGQEVVVVDTPSFNQMLDVEKDPS RLEEEVKRCLSCCEKGDTFFVLVFQLGRFTEEDKTAVAK LEAIFGADFTKYAIMLFTRKEDLGAGNLEDFMKNSDNKA LRRIFKKCGRRVCAFNNKETGQAQETQVKALLTKVNDLR KESGWSGYPHTQENVSKLIKNVQEMSQAEKLLKNLIGILQ

Database cross reference

RefSeq Protein accession:NP_783161
RefSeq Protein gi:28416956

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005783;C:endoplasmic reticulum;IEA:UniProtKB-SubCell. GO:0005794;C:Golgi apparatus;IEA:UniProtKB-SubCell. GO:0005739;C:mitochondrion;IEA:UniProtKB-SubCell.

GO-F

GO:0005525;F:GTP binding;IEA:UniProtKB-KW.