HuLPr24384

Uniprot ID

GSG1_HUMAN

Uniprot Acc

Q2KHT4;Q8N4M3;Q8NBR4;Q8NBS0;Q8NBT1;Q96LP9;Q96SI6;Q9BUY4;

Protein name

Germ cell-specific gene 1 protein

Comment

FUNCTION:May cause the redistribution of PAPOLB from the cytosol to the endoplasmic reticulum (By similarity).||SUBUNIT:Interacts with PAPOLB (By similarity).||SUBCELLULAR LOCATION:Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Note=Colocalizes with PAPOLB in the endoplasmic reticulum (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=8; Name=1; IsoId=Q2KHT4-1; Sequence=Displayed; Name=2; IsoId=Q2KHT4-2; Sequence=VSP 032997; Name=3; IsoId=Q2KHT4-3; Sequence=VSP 032993; Name=4; IsoId=Q2KHT4-4; Sequence=VSP 032993, VSP 032994; Name=5; IsoId=Q2KHT4-5; Sequence=VSP 032993, VSP 032997; Name=6; IsoId=Q2KHT4-6; Sequence=VSP 032992, VSP 032993; Name=7; IsoId=Q2KHT4-7; Sequence=VSP 032992, VSP 032995; Name=8; IsoId=Q2KHT4-8; Sequence=VSP 032993, VSP 032996;||SIMILARITY:Belongs to the GSG1 family.||SEQUENCE CAUTION:Sequence=AAH01796.1; Type=Erroneous initiation; Sequence=AAH33854.1; Type=Erroneous initiation;

Subcellular localization

Endoplasmic reticulum membrane;Multi-pass membrane protein(By similarity).

Gene name

germ cell associated 1

Protein sequence

MAKMELSKAFSGQRTLLSAILSMLSLSFSTTSLLSNYWFV GTQKVPKPLCEKGLAAKCFDMPVSLDGDTNTSTQEVVQY NWETGDDRFSFRSFRSGMWLSCEETVEEPALLHPQSWKQ FRALRSSGTAAAKGERCRSFIELTPPAKREILWLSLGTQ ITYIGLQFISFLLLLTDLLLTGNPACGLKLSAFAAVSSV LSGLLGMVAHMMYSQVFQATVNLGPEDWRPHVWNYGWAF YMAWLSFTCCMASAVTTFNTYTRMVLEFKCKHSKSFKEN PNCLPHHHQCFPRRLSSAAPTVGPLTSYHQYHNQPIHSV SEGVDFYSELRNKGFQRGASQELKEAVRSSVEEEQC

Database cross reference

RefSeq Protein accession:NP_001074023
RefSeq Protein gi:123317872

HLPP validation

Yes/No

Yes

Project name

French Liver;

GO:0005789;C:endoplasmic reticulum membrane;IEA:UniProtKB-SubCell. GO:0016021;C:integral to membrane;IEA:UniProtKB-KW.