HuLPr24519

Uniprot ID

H90B2_HUMAN

Uniprot Acc

Q58FF8;

Protein name

Putative heat shock protein HSP 90-beta 2

Comment

FUNCTION:Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins (By similarity).||SUBUNIT:Homodimer (By similarity).||SUBCELLULAR LOCATION:Cytoplasm (By similarity).||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.||SIMILARITY:Belongs to the heat shock protein 90 family.||CAUTION:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.||SEQUENCE CAUTION:Sequence=AAX38250.1; Type=Erroneous initiation;

Subcellular localization

Cytoplasm(By similarity).

Gene name

heat shock protein 90kDa alpha (cytosolic), class B member 2, pseudogene

Protein sequence

MPEEVHLGEKEVETFAFQAEIAQLMSLIINTFYSNKEIFL WELISNASDALDKIRYESLTDPSKLDSGKELKIDIIPNT QEHTLTLVDTGIGMTKADLINNLGTIAKFQDQTEYLEEM QVKEVVEKHSQFLGYPITLYLEKEREKEISDGKAEEEKG EKEEENKDDEEKPKIEDVGSDEEDDSGKDKKKKTKKIKE KYIDQEELNKTKPIWTRNTEDITQEEYGEFYKSLTNDWK DHLAVRYFSVEEYVSRMKEIQKSIYYITGESKEQVANSA FVEQVWKRDSRVVYMTEPIDGYQLKEFDGKSLVSVTKEG LELPEDGEEKKRMEERKAKFENLCKFMKETLDKKVEMVT VSNRLVSSSCCIVTSTYSWTANMEQIMKA

Database cross reference

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0051082;F:unfolded protein binding;IEA:InterPro.

GO-P

GO:0006457;P:protein folding;IEA:InterPro. GO:0006950;P:response to stress;IEA:UniProtKB-KW.

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr24519

PHOSPHORYLATION

198

Y

PhosphoSitePlus

479233

LTP

N

HuLPr24519

ACETYLATION

206

K

PhosphoSitePlus

11323753

LTP

N

HuLPr24519

ACETYLATION

64

K

PhosphoSitePlus

11323755

LTP

N

HuLPr24519

PHOSPHORYLATION

177

S

PhosphoSitePlus

478293

LTP

N

HuLPr24519

PHOSPHORYLATION

48

S

PhosphoSitePlus

14736127

LTP

N

HuLPr24519

PHOSPHORYLATION

45

S

PhosphoSitePlus

14736129

LTP

N

HuLPr24519

ACETYLATION

197

K

PhosphoSitePlus

482403

LTP

N

HuLPr24519

PHOSPHORYLATION

260

Y

PhosphoSitePlus

478425

LTP

HTP

N

HuLPr24519

PHOSPHORYLATION

56

Y

PhosphoSitePlus

478450

LTP

HTP

N

HuLPr24519

PHOSPHORYLATION

261

Y

PhosphoSitePlus

478471

LTP

N

HuLPr24519

PHOSPHORYLATION

183

S

PhosphoSitePlus

3147711

LTP

HTP

N

HuLPr24519

PHOSPHORYLATION

305

S

PhosphoSitePlus

3198149

LTP

N

HuLPr24519

PHOSPHORYLATION

207

T

PhosphoSitePlus

3949337

LTP

HTP

N