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Protein basic information

LiverAtlas Protein ID

HuLPr24530

Uniprot ID

HAGHL_HUMAN

Uniprot Acc

Q6PII5;A6NCC4;D3DU64;Q59FX8;Q96BZ3;Q96NR5;Q96S11;Q9BT45;

Protein name

Hydroxyacylglutathione hydrolase-like protein

Comment

FUNCTION:Hydrolase acting on ester bonds (Potential).||COFACTOR:Binds 2 zinc ions per subunit (By similarity).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q6PII5-1; Sequence=Displayed; Name=2; IsoId=Q6PII5-2; Sequence=VSP 030054; Name=3; IsoId=Q6PII5-3; Sequence=VSP 030053, VSP 030055; Name=4; IsoId=Q6PII5-4; Sequence=VSP 030052, VSP 030056;||SIMILARITY:Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.||SEQUENCE CAUTION:Sequence=AAK61250.1; Type=Erroneous gene model prediction; Sequence=BAD92568.1; Type=Erroneous initiation; Note=Translation N-terminally shortened; Sequence=BAD92568.1; Type=Miscellaneous discrepancy; Note=Sequence of unknown origin at the C-terminus;

Gene name

hydroxyacylglutathione hydrolase-like

Protein sequence

MKVKVIPVLEDNYMYLVIEELTREAVAVDVAVPKRLLEIV GREGVSLTAVLTTHHHWDHARGNPELARLRPGLAVLGAD ERIFSLTRRLAHGEELRFGAIHVRCLLTPGHTAGHMSYF LWEDDCPDPPALFSGDALSVAGCGSCLEGSAQQMYQSLA ELGTLPPETKVFCGHEHTLSNLEFAQKVEPCNDHVRAKL SWAKARPLSRRGKRVGGEGTGFGVGGALRQGLMVTGACG HSRRGMRMTCPLCRRLWARSASTTPSCGWREYGCCPGAS TVTWTLRKASGDCVLG

Database cross reference

RefSeq Protein accession:NP_115680
RefSeq Protein gi:14150041

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Human Liver Organelles;Chinese Liver;

Ontology annotation

GO-F

GO:0016787;F:hydrolase activity;IEA:UniProtKB-KW. GO:0046872;F:metal ion binding;IEA:UniProtKB-KW.