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Protein basic information

LiverAtlas Protein ID

HuLPr24848

Uniprot ID

HS905_HUMAN

Uniprot Acc

Q58FG0;

Protein name

Putative heat shock protein HSP 90-alpha A5

Comment

FUNCTION:Putative molecular chaperone that may promote the maturation, structural maintenance and proper regulation of specific target proteins (By similarity).||SUBUNIT:Homodimer (By similarity).||SUBCELLULAR LOCATION:Cytoplasm (By similarity).||DOMAIN:The TPR repeat-binding motif mediates interaction with TPR repeat-containing proteins (By similarity).||SIMILARITY:Belongs to the heat shock protein 90 family.||CAUTION:Despite classification as a pseudogene, the existence of this protein is supported by unambiguous mass spectrometry evidence.

Subcellular localization

Cytoplasm(By similarity).

Gene name

heat shock protein 90kDa alpha (cytosolic), class A member 5, pseudogene

Protein sequence

MGFHHVGQAGLELLTSGHPALERRPEYLEERRIKEIVKKH SQFIGYPITLFVEKKRNKQVSDAEAEKKEDKRKKKKESN DKPEIEDVGSDEEEEKKDADKKKKKSKEKYIDQELNKTK PIWTRNPDAITNEEYGEFHQSLTNNWEDHLAVKHFSVEG QLEELKDSRRVMKANQKHIYYITGETKDQVANSAFVECL QKHGLEVIYMIELIDKYCVQQLKELESKTVVSVAKEGLE LPEDEEEKKKQEEKKTKFENLCKIMKDMLEKKVKKVVVS NCMEDPQRHTNKIYRMIKLGLGVDEYDPTANDINAAITK EMPPLRGGDDTSRMEEVGGSG

Database cross reference


Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell.

GO-F

GO:0005524;F:ATP binding;IEA:UniProtKB-KW. GO:0051082;F:unfolded protein binding;IEA:InterPro.

GO-P

GO:0006457;P:protein folding;IEA:InterPro. GO:0006950;P:response to stress;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr24848

PHOSPHORYLATION

205

Y

PhosphoSitePlus

13310197

LTP

N

HuLPr24848

PHOSPHORYLATION

117

T

PhosphoSitePlus

18010685

LTP

N

HuLPr24848

PHOSPHORYLATION

300

Y

PhosphoSitePlus

18010687

LTP

N

HuLPr24848

PHOSPHORYLATION

177

Y

PhosphoSitePlus

11455845

LTP

N