Protein basic information
LiverAtlas Protein ID |
HuLPr24994 |
Uniprot ID |
|
Uniprot Acc |
Q6UXL0;Q6P438;Q8TAJ7; |
Protein name |
Interleukin-20 receptor subunit beta |
Comment |
FUNCTION:The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.||SUBUNIT:Heterodimer with IL20RA and heterodimer with IL22RA1.||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (By similarity).||TISSUE SPECIFICITY:Widely expressed with highest levels in skin and testis. Highly expressed in psoriatic skin.||SIMILARITY:Belongs to the type II cytokine receptor family.||SIMILARITY:Contains 2 fibronectin type-III domains. |
Subcellular localization |
Membrane;Single-pass type I membrane protein(By similarity). |
Gene name |
|
Protein sequence
|
MQTFTMVLEEIWTSLFMWFFYALIPCLLTDEVAILPAPQN LSVLSTNMKHLLMWSPVIAPGETVYYSVEYQGEYESLYT SHIWIPSSWCSLTEGPECDVTDDITATVPYNLRVRATLG SQTSAWSILKHPFNRNSTILTRPGMEITKDGFHLVIELE DLGPQFEFLVAYWRREPGAEEHVKMVRSGGIPVHLETME PGAAYCVKAQTFVKAIGRYSAFSQTECVEVQGEAIPLVL ALFAFVGFMLILVVVPLFVWKMGRLLQYSCCPVVVLPDT LKITNSPQKLISCRREEVDACATAVMSPEELLRAWIS |
Database cross reference |
RefSeq Protein accession:NP_653318
|
Liver relevance
HLPP validation |
Yes/No |
Yes |
Project name |
Chinese Liver;French Liver; |
Ontology annotation
GO-C |
GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. |
GO-F |
GO:0004872;F:receptor activity;IEA:UniProtKB-KW. |
Pathway
Pathway name |