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Protein basic information

LiverAtlas Protein ID

HuLPr25433

Uniprot ID

ISLR_HUMAN

Uniprot Acc

O14498;

Protein name

Immunoglobulin superfamily containing leucine-rich repeat protein

Comment

SUBCELLULAR LOCATION:Secreted (Potential).||TISSUE SPECIFICITY:Expressed in various tissues including retina, heart, skeletal muscle, prostate, ovary, small intestine, thyroid, adrenal cortex, testis, stomach and spinal cord.||DEVELOPMENTAL STAGE:Expressed in fetal lung and kidney.||SIMILARITY:Contains 1 Ig-like (immunoglobulin-like) domain.||SIMILARITY:Contains 5 LRR (leucine-rich) repeats.||SIMILARITY:Contains 1 LRRCT domain.||SIMILARITY:Contains 1 LRRNT domain.

Subcellular localization

Secreted(Potential).

Gene name

immunoglobulin superfamily containing leucine-rich repeat

Protein sequence

MQELHLLWWALLLGLAQACPEPCDCGEKYGFQIADCAYRD LESVPPGFPANVTTLSLSANRLPGLPEGAFREVPLLQSL WLAHNEIRTVAAGALASLSHLKSLDLSHNLISDFAWSDL HNLSALQLLKMDSNELTFIPRDAFRSLRALRSLQLNHNR LHTLAEGTFTPLTALSHLQINENPFDCTCGIVWLKTWAL TTAVSIPEQDNIACTSPHVLKGTPLSRLPPLPCSAPSVQ LSYQPSQDGAELRPGFVLALHCDVDGQPAPQLHWHIQIP SGIVEITSPNVGTDGRALPGTPVASSQPRFQAFANGSLL IPDFGKLEEGTYSCLATNELGSAESSVDVALATPGEGGE DTLGRRFHGKAVEGKGCYTVDNEVQPSGPEDNVVIIYLS RAGNPEAAVAEGVPGQLPPGLLLLGQSLLLFFFLTSF

Database cross reference

RefSeq Protein accession:NP_005536
RefSeq Protein gi:5031809

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Fetal Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005576;C:extracellular region;IEA:UniProtKB-SubCell.

GO-P

GO:0007155;P:cell adhesion;TAS:ProtInc.