Protein basic information
| LiverAtlas Protein ID |
HuLPr25502 |
|
Uniprot ID |
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Uniprot Acc |
Q92613;Q6IE79; |
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Protein name |
Protein Jade-3 |
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Comment |
FUNCTION:Component of the HBO1 complex which has a histone H4- specific acetyltransferase activity, a reduced activity toward histone H3 and is responsible for the bulk of histone H4 acetylation in vivo.||SUBUNIT:Component of the HBO1 complex composed at least of ING4 or ING5, MYST2/HBO1, MEAF6, and one of PHF15, PHF16 and PHF17.||TISSUE SPECIFICITY:Ubiquitously expressed, with highest levels in placenta and uterus.||INDUCTION:By estradiol in estrogen-responsive breast cancer cells.||SIMILARITY:Belongs to the JADE family.||SIMILARITY:Contains 1 PHD-type zinc finger.||SEQUENCE CAUTION:Sequence=BAA13205.2; Type=Erroneous initiation; |
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Gene name |
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Protein sequence
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MKRHRPVSSSDSSDESPSTSFTSGSMYRIKSKIPNEHKKP AEVFRKDLISAMKLPDSHHINPDSYYLFADTWKEEWEKG VQVPASPDTVPQPSLRIIAEKVKDVLFIRPRKYIHCSSP DTTEPGYINIMELAASVCRYDLDDMDIFWLQELNEDLAE MGCGPVDENLMEKTVEVLERHCHENMNHAIETEEGLGIE YDEDVICDVCRSPDSEEGNDMVFCDKCNVCVHQACYGIL KVPEGSWLCRSCVLGIYPQCVLCPKKGGALKTTKTGTKW AHVSCALWIPEVSIACPERMEPITKISHIPPSRWALVCN LCKLKTGACIQCSIKSCITAFHVTCAFEHGLEMKTILDE GDEVKFKSYCLKHSQNRQKLGEAEYPHHRAKEQSQAKSE KTSLRAQKLRELEEEFYSLVRVEDVAAELGMPTLAVDFI YNYWKLKRKSNFNKPLFPPKEDEENGLVQPKEESIHTRM RMFMHLRQDLERVRNLCYMISRREKLKLSHNKIQEQIFG LQVQLLNQEIDAGLPLTNALENSLFYPPPRITLKLKMPK STPEDHRNSSTETDQQPHSPDSSSSVHSIRNMQVPQESL EMRTKSYPRYPLESKNNRLLASLSHSRSEAKESSPAWRT PSSECYHGQSLGKPLVLQAALHGQSSIGNGKSQPNSKFA KSNGLEGSWSGNVTQKDSSSEMFCDQEPVFSPHLVSQGS FRKSTVEHFSRSFKETTNRWVKNTEDLQCYVKPTKNMSP KEQFWGRQVLRRSAGRAPYQENDGYCPDLELSDSEAESD GNKEKVRVRKDSSDRENPPHDSRRDCHGKSKTHPLSHSSMQR |
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Database cross reference |
RefSeq Protein accession:NP_001070913
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Chinese Liver;Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0000123;C:histone acetyltransferase complex;IDA:UniProtKB. |
|
GO-F |
GO:0008270;F:zinc ion binding;IEA:InterPro. |
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GO-P |
GO:0043966;P:histone H3 acetylation;IDA:UniProtKB. GO:0043983;P:histone H4-K12 acetylation;IDA:UniProtKB. GO:0043981;P:histone H4-K5 acetylation;IDA:UniProtKB. GO:0043982;P:histone H4-K8 acetylation;IDA:UniProtKB. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr25502 |
PHOSPHORYLATION |
548 |
S |
Phospho-ELM |
HTP |
N |
 
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
566 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
774 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
776 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
780 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
85 |
S |
Phospho-ELM |
HTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
433 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
608 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
85 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
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HuLPr25502 |
ACETYLATION |
461 |
K |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr25502 |
ACETYLATION |
735 |
K |
PhosphoSitePlus |
LTP |
N |
|
|
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HuLPr25502 |
ACETYLATION |
30 |
K |
PhosphoSitePlus |
LTP |
N |
|
|
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HuLPr25502 |
ACETYLATION |
638 |
K |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
27 |
Y |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr25502 |
ACETYLATION |
32 |
K |
PhosphoSitePlus |
HTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
566 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
774 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
776 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr25502 |
PHOSPHORYLATION |
780 |
S |
PhosphoSitePlus |
LTP |
N |
|
|
|
HuLPr25502 |
ACETYLATION |
38 |
K |
PhosphoSitePlus |
HTP |
N |
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