Protein basic information
| LiverAtlas Protein ID |
HuLPr25592 |
|
Uniprot ID |
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Uniprot Acc |
Q6UXG2;Q08AE6;Q5T5C9;Q5T5D0;Q5T5D1;Q9P2M2; |
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Protein name |
UPF0577 protein KIAA1324 |
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Comment |
FUNCTION:May play a role as a marker of hyperestrogenic state and estrogen-related type I endometrial carcinoma.||SUBCELLULAR LOCATION:Membrane; Single-pass type I membrane protein (Potential).||ALTERNATIVE PRODUCTS:Event=Alternative splicing; Named isoforms=4; Name=1; IsoId=Q6UXG2-1; Sequence=Displayed; Name=2; IsoId=Q6UXG2-2; Sequence=VSP 025116; Name=3; IsoId=Q6UXG2-3; Sequence=VSP 025115; Name=4; IsoId=Q6UXG2-4; Sequence=VSP 025117;||TISSUE SPECIFICITY:Expressed in normal endometrium but overexpressed in endometroid tumors.||INDUCTION:By estrogen replacement therapy.||SIMILARITY:Belongs to the UPF0577 family.||SEQUENCE CAUTION:Sequence=CAI13596.1; Type=Erroneous gene model prediction; Sequence=CAI13597.1; Type=Erroneous gene model prediction; Sequence=CAI13598.1; Type=Erroneous gene model prediction; Sequence=CAI22280.1; Type=Erroneous gene model prediction; |
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Subcellular localization |
Membrane;Single-pass type I membrane protein(Potential). |
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Gene name |
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Protein sequence
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MAEPGHSHHLSARVRGRTERRIPRLWRLLLWAGTAFQVTQ GTGPELHACKESEYHYEYTACDSTGSRWRVAVPHTPGLC TSLPDPIKGTECSFSCNAGEFLDMKDQSCKPCAEGRYSL GTGIRFDEWDELPHGFASLSANMELDDSAAESTGNCTSS KWVPRGDYIASNTDECTATLMYAVNLKQSGTVNFEYYYP DSSIIFEFFVQNDQCQPNADDSRWMKTTEKGWEFHSVEL NRGNNVLYWRTTAFSVWTKVPKPVLVRNIAITGVAYTSE CFPCKPGTYADKQGSSFCKLCPANSYSNKGETSCHQCDP DKYSEKGSSSCNVRPACTDKDYFYTHTACDANGETQLMY KWAKPKICSEDLEGAVKLPASGVKTHCPPCNPGFFKTNN STCQPCPYGSYSNGSDCTRCPAGTEPAVGFEYKWWNTLP TNMETTVLSGINFEYKGMTGWEVAGDHIYTAAGASDNDF MILTLVVPGFRPPQSVMADTENKEVARITFVFETLCSVN CELYFMVGVNSRTNTPVETWKGSKGKQSYTYIIEENTTT SFTWAFQRTTFHEASRKYTNDVAKIYSINVTNVMNGVAS YCRPCALEASDVGSSCTSCPAGYYIDRDSGTCHSCPTNT ILKAHQPYGVQACVPCGPGTKNNKIHSLCYNDCTFSRNT PTRTFNYNFSALANTVTLAGGPSFTSKGLKYFHHFTLSL CGNQGRKMSVCTDNVTDLRIPEGESGFSKSITAYVCQAV IIPPEVTGYKAGVSSQPVSLADRLIGVTTDMTLDGITSP AELFHLESLGIPDVIFFYRSNDVTQSCSSGRSTTIRVRC SPQKTVPGSLLLPGTCSDGTCDGCNFHFLWESAAACPLC SVADYHAIVSSCVAGIQKTTYVWREPKLCSGGISLPEQR VTICKTIDFWLKVGISAGTCTAILLTVLTCYFWKKNQKL EYKYSKLVMNATLKDCDLPAADSCAIMEGEDVEDDLIFT SKKSLFGKIKSFTSKRTPDGFDSV |
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Database cross reference |
RefSeq Protein accession:NP_065826
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Liver relevance
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HLPP validation |
Yes/No |
Yes |
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Project name |
Human Liver Organelles; |
Ontology annotation
| GO-C |
GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. |
Post-translational modification
| LiverAtlas Protein ID |
MOD type1 |
Position1 |
Residue1 |
Source name1 |
source ID1 |
Source method |
HLPP validation1 (Yes/no) |
Quality score |
|
HuLPr25592 |
PHOSPHORYLATION |
756 |
S |
PhosphoSitePlus |
LTP |
N |
 
|
|
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HuLPr25592 |
ACETYLATION |
254 |
K |
PhosphoSitePlus |
LTP |
N |
|
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|
HuLPr25592 |
ACETYLATION |
279 |
K |
PhosphoSitePlus |
LTP |
N |
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