HuLPr26487

Uniprot ID

LPLC3_HUMAN

Uniprot Acc

P59826;Q5TDX7;

Protein name

Long palate, lung and nasal epithelium carcinoma-associated protein 3

Comment

FUNCTION:May have the capacity to recognize and bind specific classes of odorants. May act as a carrier molecule, transporting odorants across the mucus layer to access receptor sites. May serve as a primary defense mechanism by recognizing and removing potentially harmful odorants or pathogenic microorganisms from the mucosa or clearing excess odorant from mucus to enable new odorant stimuli to be received (By similarity).||INTERACTION:P42224:STAT1; NbExp=1; IntAct=EBI-1055244, EBI-1057697;||SUBCELLULAR LOCATION:Secreted (By similarity). Cytoplasm. Note=According to PubMed:12837268, it is cytoplasmic.||TISSUE SPECIFICITY:Detected in nasal septal epithelium.||SIMILARITY:Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family.

Subcellular localization

Secreted(By similarity).Cytoplasm.

Gene name

chromosome 20 open reading frame 185

Protein sequence

MQPVMLALWSLLLLWGLATPCQELLETVGTLARIDKDELG KAIQNSLVGEPILQNVLGSVTAVNRGLLGSGGLLGGGGL LGHGGVFGVVEELSGLKIEELTLPKVLLKLLPGFGVQLS LHTKVGMHCSGPLGGLLQLAAEVNVTSRVALAVSSRGTP ILILKRCSTLLGHISLFSGLLPTPLFGVVEQMLFKVLPG LLCPVVDSVLGVVNELLGAVLGLVSLGALGSVEFSLATL PLISNQYIELDINPIVKSVAGDIIDFPKSRAPAKVPPKK DHTSQVMVPLYLFNTTFGLLQTNGALDMDITPELVPSDV PLTTTDLAALLPEALGKLPLHQQLLLFLRVREAPTVTLH NKKALVSLPANIHVLFYVPKGTPESLFELNSVMTVRAQL APSATKLHISLSLERLSVKVASSFTHAFDGSRLEEWLSH VVGAVYAPKLNVALDVGIPLPKVLNINFSNSVLEIVENAVVLTVAS

Database cross reference

RefSeq Protein accession:NP_872599
RefSeq Protein gi:32964823

HLPP validation

Yes/No

Yes

Project name

French Liver;

GO:0005737;C:cytoplasm;IDA:UniProtKB. GO:0005576;C:extracellular region;IEA:UniProtKB-SubCell.

GO-F

GO:0008289;F:lipid binding;IEA:InterPro. GO:0005515;F:protein binding;IPI:IntAct.

GO-P

GO:0045087;P:innate immune response;NAS:UniProtKB.