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Protein basic information

LiverAtlas Protein ID

HuLPr26821

Uniprot ID

MAGG1_HUMAN

Uniprot Acc

Q96MG7;Q8IW16;Q8TEI6;Q9H214;

Protein name

Melanoma-associated antigen G1

Comment

FUNCTION:Growth suppressor that facilitates the entry of the cell into cell cycle arrest (By similarity).||SUBUNIT:Binds the C-terminus of E2F1 and NGFR (By similarity).||SUBCELLULAR LOCATION:Cytoplasm (By similarity). Nucleus (By similarity).||TISSUE SPECIFICITY:Ubiquitous.||PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.||SIMILARITY:Contains 1 MAGE domain.||SEQUENCE CAUTION:Sequence=AAH41166.2; Type=Erroneous initiation; Sequence=BAB84964.1; Type=Frameshift; Positions=290;

Subcellular localization

Cytoplasm(By similarity).Nucleus(By similarity).

Gene name

necdin-like 2

Protein sequence

MLQKPRNRGRSGGQAERDRDWSHSGNPGASRAGEDARVLR DGFAEEAPSTSRGPGGSQGSQGPSPQGARRAQAAPAVGP RSQKQLELKVSELVQFLLIKDQKKIPIKRADILKHVIGD YKDIFPDLFKRAAERLQYVFGYKLVELEPKSNTYILINT LEPVEEDAEMRGDQGTPTTGLLMIVLGLIFMKGNTIKET EAWDFLRRLGVYPTKKHLIFGDPKKLITEDFVRQRYLEY RRIPHTDPVDYEFQWGPRTNLETSKMKVLKFVAKVHNQD PKDWPAQYCEALADEENRARPQPSGPAPSS

Database cross reference

RefSeq Protein accession:NP_619649
RefSeq Protein gi:20162572

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0005737;C:cytoplasm;IEA:UniProtKB-SubCell. GO:0005634;C:nucleus;IEA:UniProtKB-SubCell.

GO-P

GO:0040008;P:regulation of growth;IEA:UniProtKB-KW.

Post-translational modification

LiverAtlas Protein ID

MOD type1

Position1

Residue1

Source name1

source ID1

Source method

HLPP validation1 (Yes/no)

Quality score

HuLPr26821

PHOSPHORYLATION

57

S

Phospho-ELM

20668

HTP

N

HuLPr26821

PHOSPHORYLATION

60

S

Phospho-ELM

20669

HTP

N

HuLPr26821

PHOSPHORYLATION

64

S

Phospho-ELM

38183

HTP

N

HuLPr26821

PHOSPHORYLATION

304

S

Phospho-ELM

6442

HTP

N

HuLPr26821

PHOSPHORYLATION

60

S

PhosphoSitePlus

482131

LTP

N

HuLPr26821

PHOSPHORYLATION

246

Y

PhosphoSitePlus

3972590

LTP

N

HuLPr26821

PHOSPHORYLATION

304

S

PhosphoSitePlus

453667

LTP

HTP

N

HuLPr26821

PHOSPHORYLATION

51

S

PhosphoSitePlus

5498340

LTP

N

HuLPr26821

PHOSPHORYLATION

64

S

PhosphoSitePlus

3209487

LTP

HTP

N

HuLPr26821

PHOSPHORYLATION

57

S

PhosphoSitePlus

477955

LTP

HTP

N

Pathway

Pathway name

p75(NTR)-mediated_signaling