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Protein basic information

LiverAtlas Protein ID

HuLPr27320

Uniprot ID

MOT11_HUMAN

Uniprot Acc

Q8NCK7;

Protein name

Monocarboxylate transporter 11

Comment

FUNCTION:Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates (By similarity).||SUBCELLULAR LOCATION:Cell membrane; Multi-pass membrane protein (Potential).||SIMILARITY:Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.||CAUTION:It is uncertain whether Met-1 or Met-25 is the initiator.

Subcellular localization

Cell membrane;Multi-pass membrane protein(Potential).

Gene name

solute carrier family 16, member 11 (monocarboxylic acid transporter 11)

Protein sequence

MPAPQRKHRRGGFSHRCFPTPQTAMTPQPAGPPDGGWGWV VAAAAFAINGLSYGLLRSLGLAFPDLAEHFDRSAQDTAW ISALALAVQQAASPVGSALSTRWGARPVVMVGGVLASLG FVFSAFASDLLHLYLGLGLLAGFGWALVFAPALGTLSRY FSRRRVLAVGLALTGNGASSLLLAPALQLLLDTFGWRGA LLLLGAITLHLTPCGALLLPLVLPGDPPAPPRSPLAALG LSLFTRRAFSIFALGTALVGGGYFVPYVHLAPHALDRGL GGYGAALVVAVAAMGDAGARLVCGWLADQGWVPLPRLLA VFGALTGLGLWVVGLVPVVGGEESWGGPLLAAAVAYGLS AGSYAPLVFGVLPGLVGVGGVVQATGLVMMLMSLGGLLG PPLSGFLRDETGDFTASFLLSGSLILSGSFIYIGLPRAL PSCGPASPPATPPPETGELLPAPQAVLLSPGGPGSTLDTTC

Database cross reference

RefSeq Protein accession:NP_699188
RefSeq Protein gi:23503293

Liver relevance

HLPP validation

Yes/No

Yes

Project name

Chinese Liver;French Liver;Human Liver Organelles;

Ontology annotation

GO-C

GO:0016021;C:integral to membrane;IEA:UniProtKB-KW. GO:0005886;C:plasma membrane;IEA:UniProtKB-SubCell.

GO-F

GO:0015293;F:symporter activity;IEA:UniProtKB-KW.