HuLPr27442

Uniprot ID

MT1F_HUMAN

Uniprot Acc

P04733;Q9UI97;

Protein name

Metallothionein-1F

Comment

FUNCTION:Metallothioneins have a high content of cysteine residues that bind various heavy metals; these proteins are transcriptionally regulated by both heavy metals and glucocorticoids.||SUBUNIT:Monomer.||DOMAIN:Class I metallothioneins contain 2 metal-binding domains:four divalent ions are chelated within cluster A of the alpha domain and are coordinated via cysteinyl thiolate bridges to 11 cysteine ligands. Cluster B, the corresponding region within the beta domain, can ligate three divalent ions to 9 cysteines.||SIMILARITY:Belongs to the metallothionein superfamily. Type 1 family.||SEQUENCE CAUTION:Sequence=AAF23355.1; Type=Erroneous initiation;

Gene name

metallothionein 1F

Protein sequence

MDPNCSCAAGVSCTCAGSCKCKECKCTSCKKSCCSCCPVG CSKCAQGCVCKGASEKCSCCD

Database cross reference

RefSeq Protein accession:NP_005940
RefSeq Protein gi:28866947

HLPP validation

Yes/No

Yes

Project name

French Liver;

GO:0005737;C:cytoplasm;NAS:UniProtKB.

GO-F

GO:0046870;F:cadmium ion binding;NAS:UniProtKB. GO:0005507;F:copper ion binding;NAS:UniProtKB. GO:0008270;F:zinc ion binding;NAS:UniProtKB.

EGFR1